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Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis. Journal of Neuroinflammation 62.
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Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 63.
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Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 64.
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Delivery of mtZFNs into Early Mouse Embryos. Methods Mol Biol 65.
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Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation. J Cell Biol (2018)
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AGEpy: a Python package for computational biology. bioRxiv, S. 450890 (2018)
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Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification. Nat Cell Biol 68.
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Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD. Acta Neuropathol 69.
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TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy, S. 1 - 51 (2018)
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Serine is the major residue for ADP-ribosylation upon DNA damage. Elife 72.
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Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy. EMBO J (2018)
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Survival analysis with delayed entry in selected families with application to human longevity. Stat Methods Med Res 74.
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PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. The EMBO Journal 75.
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A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency. J Pathol 76.
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10 (1), S. 22 - 31 (2018)
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. EMBO Mol Med 77.
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Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins. Nature Communications 78.
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Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 79.
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Nucleolar Function in Lifespan Regulation. Trends Cell Biol (2018)
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Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance. Nat Commun