Wissenschaftliche Publikationen

Campoy, J. A.; Sun, H.; Goel, M.; Jiao, W. B.; Folz-Donahue, K.; Wang, N.; Rubio, M.; Liu, C.; Kukat, C.; Ruiz, D. et al.; Huettel, B.; Schneeberger, K.: Gamete binning: chromosome-level and haplotype-resolved genome assembly enabled by high-throughput single-cell sequencing of gamete genomes. Genome Biol 21 (1), S. 306 (2020)

Mkrtchyan, G. V.; Abdelmohsen, K.; Andreux, P.; Bagdonaite, I.; Barzilai, N.; Brunak, S.; Cabreiro, F.; de Cabo, R.; Campisi, J.; Cuervo, A. M. et al.; Demaria, M.; Ewald, C. Y.; Fang, E. F.; Faragher, R.; Ferrucci, L.; Freund, A.; Silva-García, C. G.; Georgievskaya, A.; Gladyshev, V. N.; Glass, D. J.; Gorbunova, V.; de Grey, A.; He, W. W.; Hoeijmakers, J.; Hoffmann, E.; Horvath, S.; Houtkooper, R. H.; Jensen, M. K.; Jensen, M. B.; Kane, A.; Kassem, M.; de Keizer, P.; Kennedy, B.; Karsenty, G.; Lamming, D. W.; Lee, K. F.; MacAulay, N.; Mamoshina, P.; Mellon, J.; Molenaars, M.; Moskalev, A.; Mund, A.; Niedernhofer, L.; Osborne, B.; Pak, H. H.; Parkhitko, A.; Raimundo, N.; Rando, T. A.; Rasmussen, L. J.; Reis, C.; Riedel, C. G.; Franco-Romero, A.; Schumacher, B.; Sinclair, D. A.; Suh, Y.; Taub, P. R.; Toiber, D.; Treebak, J. T.; Valenzano, D. R.; Verdin, E.; Vijg, J.; Young, S.; Zhang, L.; Bakula, D.; Zhavoronkov, A.; Scheibye-Knudsen, M.: ARDD 2020: from aging mechanisms to interventions. Aging (Albany NY) 12 (24), S. 24484 - 24503 (2020)

Bonekamp, N.; Peter, B.; Hillen, H. S.; Felser, A.; Bergbrede, T.; Choidas, A.; Horn, M.; Unger, A.; Di Lucrezia, R.; Atanassov, I. et al.; Li, X.; Koch, U.; Menninger, S.; Boros, J.; Habenberger, P.; Giavalisco, P.; Cramer, P.; Denzel, M. S.; Nussbaumer, P.; Klebl, B.; Falkenberg, M.; Gustafsson, C. M.; Larsson, N.G.: Small-molecule inhibitors of human mitochondrial DNA transcription. Nature 588 (7839), S. 712 - 716 (2020)

Basu, S.; Xie, X.; Uhler, J. P.; Hedberg-Oldfors, C.; Milenkovic, D.; Baris, O. R.; Kimoloi, S.; Matic, S.; Stewart, J.; Larsson, N. G. et al.; Wiesner, R. J.; Oldfors, A.; Gustafsson, C. M.; Falkenberg, M.; Larsson, E.: Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing. PLoS Genet 16 (12), S. e1009242 (2020)

Cipullo, M.; Pearce, S. F.; Lopez Sanchez, I. G.; Gopalakrishna, S.; Kruger, A.; Schober, F.; Busch, J. D.; Li, X.; Wredenberg, A.; Atanassov, I. et al.; Rorbach, J.: Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. Nucleic Acids Res 49 (1), S. 354 - 370 (2020)

Bjedov, I.; Cocheme, H. M.; Foley, A.; Wieser, D.; Woodling, N. S.; Castillo-Quan, J. I.; Norvaisas, P.; Lujan, C.; Regan, J. C.; Toivonen, J. M. et al.; Murphy, M. P.; Thornton, J.; Kinghorn, K. J.; Neufeld, T. P.; Cabreiro, F.; Partridge, L.: Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila. PLoS Genet 16 (11), S. e1009083 (2020)

Pearce, S. F.; Cipullo, M.; Chung, B.; Brierley, I.; Rorbach, J.: Mitoribosome Profiling from Human Cell Culture: A High Resolution View of Mitochondrial Translation. Methods Mol Biol 2192, S. 183 - 196 (2020)

Bonfiglio, J. J.; Leidecker, O.; Dauben, H.; Longarini, E. J.; Colby, T.; San Segundo-Acosta, P.; Perez, K. A.; Matic, I.: An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation. Cell 183 (4), S. 1086 - 1102 e23 (2020)

Coch, R. A.; Geisler, F.; Annibal, A.; Antebi, A.; Leube, R. E.: Identification of a Novel Link between the Intermediate Filament Organizer IFO-1 and Cholesterol Metabolism in the Caenorhabditis elegans Intestine. Int J Mol Sci 21 (21), S. 8219 (2020)

Stewart, J.: Current progress with mammalian models of mitochondrial DNA disease. J Inherit Metab Dis 44 (2), S. 325 - 342 (2020)

Wang, Z.; Liu, F.; Fan, N.; Zhou, C.; Li, D.; MacVicar, T.; Dong, Q.; Bruns, C. J.; Zhao, Y.: Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies. Front Oncol 10, S. 589508 (2020)

Bergami, M.; Motori, E.: Reweaving the Fabric of Mitochondrial Contact Sites in Astrocytes. Front Cell Dev Biol 8, S. 592651 (2020)

van den Akker, E. B.; Trompet, S.; Barkey Wolf, J. J. H.; Beekman, M.; Suchiman, H. E. D.; Deelen, J.; Asselbergs, F. W.; Boersma, E.; Cats, D.; Elders, P. M. et al.; Geleijnse, J. M.; Ikram, M. A.; Kloppenburg, M.; Mei, H.; Meulenbelt, I.; Mooijaart, S. P.; Nelissen, R.; Netea, M. G.; Penninx, B.; Slofstra, M.; Stehouwer, C. D. A.; Swertz, M. A.; Teunissen, C. E.; Terwindt, G. M.; t Hart, L. M.; van den Maagdenberg, A.; van der Harst, P.; van der Horst, I. C. C.; van der Kallen, C. J. H.; van Greevenbroek, M. M. J.; van Spil, W. E.; Wijmenga, C.; Zhernakova, A.; Zwinderman, A. H.; Sattar, N.; Jukema, J. W.; van Duijn, C. M.; Boomsma, D. I.; Reinders, M. J. T.; Slagboom, P. E.: Metabolic Age Based on the BBMRI-NL (1)H-NMR Metabolomics Repository as Biomarker of Age-related Disease. Circ Genom Precis Med 13 (5), S. 541 - 547 (2020)

Bröckelmann, P. J.; de Jong, M. R. W.; Jachimowicz, R. D.: Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma. Cells 9 (10), S. 2287 (2020)

Badimon, A.; Strasburger, H. J.; Ayata, P.; Chen, X.; Nair, A.; Ikegami, A.; Hwang, P.; Chan, A. T.; Graves, S. M.; Uweru, J. O. et al.; Ledderose, C.; Kutlu, M. G.; Wheeler, M. A.; Kahan, A.; Ishikawa, M.; Wang, Y. C.; Loh, Y. E.; Jiang, J. X.; Surmeier, D. J.; Robson, S. C.; Junger, W. G.; Sebra, R.; Calipari, E. S.; Kenny, P. J.; Eyo, U. B.; Colonna, M.; Quintana, F. J.; Wake, H.; Gradinaru, V.; Schaefer, A.: Negative feedback control of neuronal activity by microglia. Nature 586 (7829), S. 417 - 423 (2020)

Chamoli, M.; Goyala, A.; Tabrez, S. S.; Siddiqui, A. A.; Singh, A.; Antebi, A.; Lithgow, G. J.; Watts, J. L.; Mukhopadhyay, A.: Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction. Nat Commun 11 (1), S. 4865 (2020)

Mittenbühler, M. J.; Saedler, K.; Nolte, H.; Kern, L.; Zhou, J.; Qian, S. B.; Meder, L.; Ullrich, R. T.; Brüning, J. C.; Wunderlich, F. T.: Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo. Mol Metab 42, S. 101085 (2020)

Pisanti, S.; Deelen, J.; Gallina, A. M.; Caputo, M.; Citro, M.; Abate, M.; Sacchi, N.; Vecchione, C.; Martinelli, R.: Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19. J Transl Med 18 (1), S. 352 (2020)

Woodling, N. S.; Rajasingam, A.; Minkley, L. J.; Rizzo, A.; Partridge, L.: Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling. BMC Biol 18 (1), S. 124 (2020)

Motori, E.; Atanassov, I.; Kochan, S. M. V.; Folz-Donahue, K.; Sakthivelu, V.; Giavalisco, P.; Toni, N.; Puyal, J.; Larsson, N.G.: Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction. Sci Adv 6 (35), S. eaba8271 (2020)