Scientific Publications

Adriaenssens, E.; Asselbergh, B.; Rivera-Mejías, P.; Bervoets, S.; Vendredy, L.; De Winter, V.; Spaas, K.; de Rycke, R.; van Isterdael, G.; Impens, F. et al.; Langer, T.; Timmerman, V.: Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space. Nature Cell Biology (2023)

Di Sante, M.; Antonucci, S.; Pontarollo, L.; Cappellaro, I.; Segat, F.; Deshwal, S.; Greotti, E.; Grilo, L. F.; Menabò, R.; Di Lisa, F. et al.; Kaludercic, N.: Monoamine oxidase A-dependent ROS formation modulates human cardiomyocyte differentiation through AKT and WNT activation. Basic Research in Cardiology 118, 4 (2023)

Seidel, J.; Bradshaw, W.; Valenzano, D. R.: Sequencing the Immunoglobulin Heavy-Chain Locus (IgH) in Turquoise Killifish ( Nothobranchius furzeri). Cold Spring Harb Protoc (2023)

Deshwal, S.; Onishi, M.; Tatsuta, T.; Bartsch, T.; Cors, E.; Ried, K.; Lemke, K.; Nolte, H.; Giavalisco, P.; Langer, T.: Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature Cell Biology (2023)

Remes , C.; Khawaja, A.; Pearce, S. F.; Dinan, A. M.; Gopalakrishna, S.; Cipullo, M.; Kyriakidis, V.; Zhang, J.; Dopico, X. C.; Yukhnovets, O. et al.; Atanassov, I.; Firth, A. E.; Cooperman, B.; Rorbach, J.: Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria. Nucleic Acids Research (2023)

Dalmasso, M. C.; Arán, M.; Galeano, P.; Perin, S.; Giavalisco, P.; Martino Adami, P. V.; Novack, G. V.; Castaño, E. M.; Cuello, A. C.; Scherer, M. et al.; Maier, W.; Wagner, M.; Riedel-Heller, S.; Ramirez, A.; Morelli, L.: Nicotinamide as potential biomarker for Alzheimer’s disease: A translational study based on metabolomics. Frontiers in Molecular Biosciences 9 (2023)

Krüger, A.; Remes, C.; Shiriaev, D. I.; Liu, Y.; Spåhr, H.; Wibom, R.; Atanassov, I.; Nguyen, M. D.; Cooperman, B. S.; Rorbach, J.: Human mitochondria require mtRF1 for translation termination at non-canonical stop codons. Nature Communications 14, 30 (2023)

Hanssen, R.; Rigoux, L.; Albus, K.; Kretschmer, A. C.; Edwin Thanarajah, S.; Chen, W.; Hinze, Y.; Giavalisco, P.; Steculorum, S. M.; Cornely, O. A. et al.; Brüning, J. C.; Tittgemeyer, M.: Circulating uridine dynamically and adaptively regulates food intake in humans. Cell Reports Medicine 4, 100897, p. 100897 (2023)

Kuan, V.; Denaxas, S.; Patalay, P.; Nitsch, D.; Mathur, R.; Gonzalez-Izquierdo, A.; Sofat, R.; Partridge, L.; Roberts, A.; Wong, I. C. K. et al.; Hingorani, M.; Chaturvedi, N.; Hemingway, H.; Hingorani, A. D.; Alexander, D. C.; Asiimwe, I. G.; Ball, S.; Bennett, F.; Borges, M. C.; Butterworth, A.; Chaturvedi, N.; Chopade, S.; Clarkson, C.; Cox, M.; Dale, C.; Denaxas, S.; Dunca, D.; Engmann, J. E.; Fernandez-Sanles, A.; Finan, C.; Fitzpatrick, N.; Gallagher, J.; Gonzalez-Izquierdo, A.; Gratton, J.; Gross, C.; Hemingway, H.; Henry, A.; Hidajat, M.; Hingorani, A.; Hukerikar, N.; Jorgensen, A.; Joshi, R.; Katsoulis, M.; Kuan, V.; Kumar, R.; Lai, A. G.; Langenberg, C.; Lawlor, D.; Mancini, M.; Miller, D.; Ogden, M.; Ozyigit, E. B.; Patel, S.; Pirmohamed, M.; Roberts, A.; Ryan, D.; Schmidt, A. F.; Shah, A. D.; Shah, T.; Sofat, R.; Takhar, R.; Torralbo, A.; Ullah, A.; Walker, L. E.; Warwick, A.; Wheeler, E.; Wright, V. L.; Wu, H.; Zwierzyna, M.: Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. The Lancet Digital Health 5, pp. e16 - e27 (2023)

López-Otín, C.; Blasco, M. A.; Partridge, L.; Serrano, M.; Kroemer, G.: Hallmarks of aging: An expanding universe. Cell (2023)

Treaster, S.; Deelen, J.; Daane, J. M.; Murabito, J.; Karasik, D.; Harris, M. P.: Convergent genomics of longevity in rockfishes highlights the genetics of human life span variation. Science Advances 9 (2023)

Poláchová, E.; Bach, K.; Heuten, E.; Stanchev, S.; Tichá, A.; Lampe, P.; Majer, P.; Langer, T.; Lemberg, M. K.; Stříšovský, K.: Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy. Journal of Medicinal Chemistry (2022)

Jauch, A. S.; Wohlfeil, S. A.; Weller, C.; Dietsch, B.; Häfele, V.; Stojanovic, A.; Kittel, M.; Nolte, H.; Cerwenka, A.; Neumaier, M. et al.; Schledzewski, K.; Sticht, C.; Reiners-Koch, P.-S.; Goerdt, S.; Géraud, C.: Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis. Cancer Cell International 22, 398 (2022)

Pouikli, A.; Maleszewska, M.; Parekh, S.; Yang, M.; Nikopoulou, C.; Bonfiglio, J. J.; Mylonas, C.; Sandoval, T.; Schumacher, A. L.; Hinze, Y. et al.; Matić, I.; Frezza, C.; Tessarz, P.: Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication. EMBO J, p. e111239 (2022)

Regan, J. C.; Lu, Y.-X.; Urena, E.; Meilenbrock, R. L.; Catterson, J. H.; Kißler, D.; Fröhlich, J.; Funk, E.; Partridge, L.: Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin. Nature aging (2), pp. 1145 - 1158 (2022)

Saini, P. K.; Dawitz, H.; Aufschnaiter, A.; Bondarev, S.; Thomas, J.; Amblard, A.; Stewart, J. B.; Thierry-Mieg, N.; Ott, M.; Pierrel, F.: The [PSI+] prion modulates cytochrome c oxidase deficiency caused by deletion of COX12. Mol Biol Cell, p. mbcE21100499 (2022)

Kuan, V.; Denaxas, S.; Patalay, P.; Nitsch, D.; Mathur, R.; Gonzalez-Izquierdo, A.; Sofat, R.; Partridge, L.; Roberts, A.; Wong, I. C. K. et al.; Hingorani, M.; Chaturvedi, N.; Hemingway, H.; Hingorani, A. D.; Multimorbidity, M.; Therapeutic Research, C.: Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. Lancet Digit Health (2022)

Flümann, R.; Hansen, J.; Pelzer, B. W.; Nieper, P.; Lohmann, T.; Kisis, I.; Riet, T.; Kohlhas, V.; Nguyen, P. H.; Peifer, M. et al.; Abedpour, N.; Bosco, G.; Thomas, R. K.; Kochanek, M.; Knufer, J.; Jonigkeit, L.; Beleggia, F.; Holzem, A.; Buttner, R.; Lohneis, P.; Meinel, J.; Ortmann, M.; Persigehl, T.; Hallek, M.; Calado, D. P.; Chmielewski, M.; Klein, S.; Gothert, J. R.; Chapuy, B.; Zevnik, B.; Wunderlich, F. T.; von Tresckow, B.; Jachimowicz, R. D.; Melnick, A. M.; Reinhardt, H. C.; Knittel, G.: Distinct genetically-determined origins of Myd88/Bcl2-driven aggressive lymphoma rationalize targeted therapeutic intervention strategies. Blood Cancer Discov (2022)

Vesting, A. J.; Jais, A.; Klemm, P.; Steuernagel, L.; Wienand, P.; Fog-Tonnesen, M.; Hvid, H.; Schumacher, A. L.; Kukat, C.; Nolte, H. et al.; Georgomanolis, T.; Altmuller, J.; Pasparakis, M.; Schmidt, A.; Kruger, M.; Supprian, M. S.; Waisman, A.; Straub, B. K.; Raschzok, N.; Bernier, M.; Birkenfeld, A. L.; Hovelmeyer, N.; Bruning, J. C.; Wunderlich, F. T.: NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Mol Metab, p. 101626 (2022)

Conte, M.; Eletto, D.; Pannetta, M.; Petrone, A. M.; Monti, M. C.; Cassiano, C.; Giurato, G.; Rizzo, F.; Tessarz, P.; Petrella, A. et al.; Tosco, A.; Porta, A.: Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis. Front Cell Infect Microbiol 12, p. 1031814 (2022)