Wissenschaftliche Publikationen

Gavriljuk, K.; Gazdag, E.-M.; Itzen, A.; Kötting, C.; Goody, R. S.; Gerwert, K.: Catalytic mechanism of a mammalian Rab.RabGAP complex in atomic detail. Proceedings of the National Academy of Sciences of the United States of America 109 (52), 1, S. 21348 - 21353 (2012)

Wolf, A.; Baumann, S.; Arndt, H.-D.; Kirschner, K. N.: Influence of thiostrepton binding on the ribosomal GTPase associated region characterized by molecular dynamics simulation. Bioorganic & Medicinal Chemistry 20 (24), 1, S. 7194 - 7205 (2012)

Baskar, B.; Wittstein, K.; Sankar, M. G.; Khedkar, V.; Schürmann, M.; Kumar, K.: Stereoselective Cascade Double-Annulations Provide Diversely Ring-Fused Tetracyclic Benzopyrones. Organic Letters 14 (23), 1, S. 5924 - 5927 (2012)

Samanta, R.; Narayan, R.; Antonchick, A. P.: Rhodium(III)-Catalyzed Direct Oxidative Cross Coupling at the C5 Position of Chromones with Alkenes. Organic Letters 14 (23), 1, S. 6108 - 6111 (2012)

Blümer, J.; Wu, Y.-W.; Goody, R. S.; Itzen, A.: Specific localization of Rabs at intracellular membranes. Biochemical Society Transactions 40 (6), 1, S. 1421 - 1425 (2012)

Gradmann, S.; Ader, C.; Heinrich, I.; Nand, D.; Dittmann, M.; Cukkemane, A.; Van Dijk, M.; Bonvin, A. M. J. J.; Engelhard, M.; Baldus, M.: Rapid prediction of multi-dimensional NMR data sets. Journal of Biomolecular NMR 54 (4), 1, S. 377 - 387 (2012)

Kalinin, S.; Peulen, T.; Sindbert, S.; Rothwell, P. J.; Berger, S.; Restle, T.; Goody, R. S.; Gohlke, H.; Seidel, C. A. M.: A toolkit and benchmark study for FRET-restrained high-precision structural modeling. Nature Methods 9 (12), 1, S. 1218 - 1225 (2012)

Ottmann, C.: Small-molecule modulators of 14-3-3 protein–protein interactions. Bioorganic & Medicinal Chemistry, Article in press, online ahead of print, S. 1 - 5 (2012)

Scolz, M.; Widlund, P. O.; Piazza, S.; Bublik, D. R.; Reber, S.; Peche, L. Y.; Ciani, Y.; Hubner, N.; Isokane, M.; Monte, M. et al.; Ellenberg, J.; Hyman, A. A.; Schneider, C.; Bird, A. W.: GTSE1 Is a Microtubule Plus-End Tracking Protein That Regulates EB1-Dependent Cell Migration. PLoS One 7 (12), S. e51259:1 - e51259:17 (2012)

Stein, M.-P.; Müller, M. P.; Wandinger-Ness, A.: Bacterial Pathogens Commandeer Rab GTPases to Establish Intracellular Niches. Traffic 13 (12), 1, S. 1565 - 1588 (2012)

Willmann, D.; Lim, S.; Wetzel, S.; Metzger, E.; Jandausch, A.; Wilk, W.; Jung, M.; Forne, I.; Imhof, A.; Janzer, A. et al.; Kirfel, J.; Waldmann, H.; Schüle, R.; Buettner, R.: Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. International Journal of Cancer 131 (11), 1, S. 2704 - 2709 (2012)

Matcha, K.; Madduri, A. V. R.; Roy, S.; Ziegler, S.; Waldmann, H.; Hirsch, A. K. H.; Minnaard, A. J.: Total Synthesis of ( -)-Doliculide, Structure–Activity Relationship Studies and Its Binding to F-Actin. ChemBioChem 13 (17), 1, S. 2537 - 2548 (2012)

Kim, B.; Eggel, A.; Tarchevskaya, S. S.; Vogel, M.; Prinz, H.; Jardetzky, T. S.: Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor. Nature 491 (7425), 1, S. 613 - 617 (2012)

Molzan, M.; Ottmann, C.: Synergistic Binding of the Phosphorylated S233- and S259-Binding Sites of C-RAF to One 14-3-3ζ Dimer. Journal of Molecular Biology 423 (4), 1, S. 486 - 495 (2012)

Samanta, R.; Bauer, J. O.; Strohmann, C.; Antonchick, A. P.: Organocatalytic, Oxidative, Intermolecular Amination and Hydrazination of Simple Arenes at Ambient Temperature. Organic Letters 14 (21), 1, S. 5518 - 5521 (2012)

Musacchio, A.; Ciliberto, A.: The spindle-assembly checkpoint and the beauty of self-destruction. Nature Structural & Molecular Biology 19 (11), 1, S. 1059 - 1061 (2012)

Mariani, L.; Chiroli, E.; Nezi, L.; Muller, H.; Piatti, S.; Musacchio, A.; Ciliberto, A.: Role of the Mad2 Dimerization Interface in the Spindle Assembly Checkpoint Independent of Kinetochores. Current Biology 22 (20), 1, S. 1900 - 1908 (2012)

Sos, M. L.; Dietlein, F.; Peifer, M.; Schöttle, J.; Balke-Want, H.; Müller, C.; Koker, M.; Richters, A.; Heynck, S.; Malchers, F. et al.; Heuckmann, J. M.; Seidel, D.; Eyers, P. A.; Ullrich, R. T.; Antonchick, A. P.; Vintonyak, V. V.; Schneider, P. M.; Ninomiya, T.; Waldmann, H.; Büttner, R.; Rauh, D.; Heukamp, L. C.; Thomas, R. K.: A framework for identification of actionable cancer genome dependencies in small cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America 109 (42), 1, S. 17034 - 17039 (2012)

De Antoni, A.; Maffini, S.; Knapp, S.; Musacchio, A.; Santaguida, S.: A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. Journal of Cell Biology 199 (2), 1, S. 269 - 284 (2012)

Kushnir, S.; Sundermann, U.; Yahiaoui, S.; Brockmeyer, A.; Janning, P.; Schulz, F.: Minimally Invasive Mutagenesis Gives Rise to a Biosynthetic Polyketide Library. Angewandte Chemie International Edition 51 (42), 1, S. 10664 - 10669 (2012)