Wissenschaftliche Publikationen

Linke, M.; Quoika, P. K.; Bramas, B.; Köfinger, J.; Hummer, G.: Complexes++: Efficient and versatile coarse-grained simulations of protein complexes and their dense solutions. The Journal of Chemical Physics 157 (20), 204802 (2022)

Laube, E.; Meier-Credo, J.; Langer, J. D.; Kühlbrandt, W.: Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Science Advances 8 (47), eadc9952 (2022)

Schmitt, D.; Bozkurt, S.; Henning-Domres, P.; Huesmann, H.; Eimer, S.; Bindila, L.; Behrends, C.; Boyle, E.; Wilfling, F.; Tascher, G. et al.; Münch, C.; Behl, C.; Kern, A.: FACS-mediated isolation of native autophagic vesicles. Autophagy (2022)

Schiller, J.; Laube, E.; Wittig, I.; Kühlbrandt, W.; Vonck, J.; Zickermann, V.: Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling. Science Advances 8 (46), eadd3855 (2022)

Oo, J. A.; Pálfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomašković, I.; Boos, F.; Izquierdo Ponce, J.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Pham, M. D.; Krishnan, J.; Baker, A. H.; Günther, S.; Ulrich, H. D.; Đikić, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell Reports: Methods 41 (7), 111670 (2022)

Schaefer, S. L.; Hummer, G.: Sublytic gasdermin-D pores captured in atomistic molecular simulations. eLife 11, e81432 (2022)

Siggel, M.; Kehl, S.; Reuter, K.; Köfinger, J.; Hummer, G.: TriMem: A parallelized hybrid Monte Carlo software for efficient simulations of lipid membranes. The Journal of Chemical Physics 157 (17), 174801 (2022)

Astashkin, R.; Kovalev, K.; Bukhdruker, S.; Vaganova, S.; Kuzmin, A.; Alekseev, A.; Balandin, T.; Zabelskii, D.; Gushchin, I.; Royant, A. et al.; Volkov, D.; Bourenkov, G.; Koonin, E.; Engelhard, M.; Bamberg, E.; Gordeliy, V.: Structural insights into light-driven anion pumping in cyanobacteria. Nature Communications 13, 6460 (2022)

Kühlbrandt, W.: Concluding remarks: Challenges and future developments in biological electron cryo-microscopy. Faraday Discussions (2022)

Vitt, S.; Prinz, S.; Eisinger, M. L.; Ermler, U.; Buckel, W.: Purification and structural characterization of the Na⁺-translocating ferredoxin: NAD⁺ reductase (Rnf) complex of Clostridium tetanomorphum. Nature Communications 13, 6315 (2022)

Cruz-León, S.; Schwierz, N.: RNA Captures More Cations than DNA: Insights from Molecular Dynamics Simulations. The Journal of Physical Chemistry B (2022)

Schleker, E. S. M.; Buschmann, S.; Xie, H.; Welsch, S.; Michel, H.; Reinhart, C.: Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules. Proceedings of the National Academy of Sciences of the United States of America 119 (43), e2202822119 (2022)

Mathioudaki, E.; Alifragis, Y.; Fouskaki, M.; Chochlakis, D.; Xie, H.; Psaroulaki, A.; Tsiotis, G.; Chaniotakis, N.: Electrochemical Antigenic Sensor for the Diagnosis of Chronic Q Fever. Current Research in Biotechnology 4, S. 537 - 543 (2022)

Lee, Y.; Haapanen, O.; Altmeyer, A.; Kühlbrandt, W.; Sharma, V.; Zickermann, V.: Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations. Nature Communications 13 (1), 6091 (2022)

Schmitt, D.; Bozkurt, S.; Henning-Domres, P.; Huesmann, H.; Eimer, S.; Bindila, L.; Behrends, C.; Boyle, E.; Wilfling, F.; Tascher, G. et al.; Münch, C.; Behl, C.; Kern, A.: Lipid and protein content profiling of isolated native autophagic vesicles. EMBO Reports, e53065 (2022)

Schulz, L.; Guo, Z.; Zarzycki, J.; Steinchen, W.; Schuller, J. M.; Heimerl, T.; Prinz, S.; Mueller-Cajar, O.; Erb, T. J.; Hochberg, G. K. A.: Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Science 378 (6616), S. 155 - 160 (2022)

Shah, V. J.; Đikić, I.: Localization matters in targeted protein degradation. Cell Chemical Biology 29 (10), S. 1465 - 1466 (2022)

Zöller, J.; Hong, S.; Eisinger, M. L.; Anderson, M.; Radloff, M.; Desch, K.; Gennis, R.; Langer, J. D.: Ligand binding and conformational dynamics of the E. coli nicotinamide nucleotide transhydrogenase revealed by hydrogen/deuterium exchange mass spectrometry. Computational and Structural Biotechnology Journal 20, S. 5430 - 5439 (2022)

Bieber, A.; Capitanio, C.; Erdmann, P. S.; Fiedler, F.; Beck, F.; Lee, C.-W.; Li, D.; Hummer, G.; Schulman, B. A.; Baumeister, W. et al.; Wilfling, F.: In situ structural analysis reveals membrane shape transitions during autophagosome formation. Proceedings of the National Academy of Sciences of the United States of America 119 (39), e2209823119 (2022)

Khera, R.; Mehdipour, A. R.; Bolla, J. R.; Kahnt, J.; Welsch, S.; Ermler, U.; Münke, C.; Robinson, C. V.; Hummer, G.; Xie, H. et al.; Michel, H.: Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism. The EMBO Journal 41 (18), e109990 (2022)