Wissenschaftliche Publikationen

Zolotarev, N.; Bayer, M.; Grosschedl, R.: EBF1 is continuously required for stabilizing local chromatin accessibility in pro-B cells. Proceedings of the National Academy of Sciences of the United States of America 119, e2210595119 (2022)

Andreani, V.; Ramamoorthy, S.; Fässler, R.; Grosschedl, R.: Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling. Journal of Experimental Medicine 220, e20220342 (2022)

Carrasco, J.; Mateos, F.; Hilgers, V.: A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation. Cell Reports 41, 111542 (2022)

Giorgetti, O. B.; Nusser, A.; Boehm, T.: Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice. Communications Biology 5, 1037 (2022)

Grzejda, D.; Mach, J.; Schweizer, J. A.; Hummel, B.; Rezansoff, A. M.; Eggenhofer, F.; Panhale, A.; Lalioti, M.-E.; Cabezas-Wallscheid, N.; Backofen, R. et al.; Felsenberg, J.; Hilgers, V.: The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity. Science Advances 8, eabo5578 (2022)

Bayer, M.; Boller, S.; Ramamoothy, S.; Zolotarev, N.; Cauchy, P.; Iwanami, N.; Mittler, G.; Boehm, T.; Grosschedl, R.: Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling. Genes and Development 36, S. 901 - 915 (2022)

Iwanami, N.; Petersen, M.; Diekhoff, D.; Boehm, T.: Clonal dynamics underlying the skewed CD4/CD8 ratio of mouse thymocytes revealed by TCR-independent barcoding. Communications Biology 5, 911 (2022)

Lenaerts, A.; Kucinski, I.; Deboutte, W.; Derecka, M.; Cauchy, P.; Manke, T.; Göttgens, B.; Grosschedl, R.: EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors. Journal of Experimental Medicine 219, e20212437 (2022)

Nagakubo, D.; Hirakawa, M.; Iwanami, N.; Boehm, T.: Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1. Scientific Reports 12, 13554 (2022)

Schuster, E.-M.; Epple, M. W.; Glaser, K. M.; Mihlan, M.; Lucht, K.; Zimmermann, J. A.; Bremser, A.; Polyzou, A.; Obier, N.; Cabezas-Wallscheid, N. et al.; Trompouki, E.; Ballabio, A.; Vogel, J.; Büscher, J. M.; Westermann, A. J.; Rambold, A.: TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages. Nature Metabolism (2022)

Mihlan, M.; Safaiyan, S.; Stecher, M.; Paterson, N.; Lämmermann, T.: Surprises from Intravital Imaging of the Innate Immune Response. Annual Review of Cell and Developmental Biology 38, S. 18.1 - 18.23 (2022)

Qiu, Z.; Guo, W.; Dong, B.; Wang, Y.; Deng, P.; Wang, C.; Liu, J.; Zhang, Q.; Grosschedl, R.; Yu, Z. et al.; Deng, J.; Wu, Y.: EBF1 promotes triple-negative breast cancer progression by surveillance of the HIF1α pathway. Proceedings of the National Academy of Sciences of the United States of America 119, e2119518119 (2022)

Zhang, Y. W.; Mess, J.; Aizarani, N.; Mishra, P.; Johnson, C.; Romero-Mulero, M. C.; Rettkowski, J.; Schönberger, K.; Obier, N.; Jäcklein, K. et al.; Woessner, N. M.; Lalioti, M.-E.; Velasco-Hernandez, T.; Sikora, K.; Wäsch, R.; Lehnertz, B.; Sauvageau, G.; Manke, T.; Menendez, P.; Walter, S. G.; Minguet, S.; Laurenti, E.; Günther, S.; Grün, D.; Cabezas-Wallscheid, N.: Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells. Nature Cell Biology (2022)

Schönberger, K.; Mitterer, M.; Büscher, J. M.; Cabezas-Wallscheid, N.: Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers. STAR Protocols 3, 101408 (2022)

Nusser, A.; Sagar; Swann, J.; Krauth, B.; Diekhoff, D.; Calderon, L.; Happe, C.; Grün, D.; Boehm, T.: Developmental dynamics of two bipotent thymic epithelial progenitor types. Nature (2022)

Hilgers, V.: Regulation of neuronal RNA signatures by ELAV/Hu proteins. Wiley interdisciplinary reviews: WIREs RNA, e1733 (2022)

Eilertz, D.; Mitterer, M.; Büscher, J. M.: automRm: An R Package for Fully Automatic LC-QQQ-MS Data Preprocessing Powered by Machine Learning. Analytical Chemistry (2022)

Jünger, F.; Ruh, D.; Strobel, D.; Michiels, R.; Huber, D.; Brandel, A.; Madl, J.; Gavrilov, A.; Mihlan, M.; Daller, C. C. et al.; Rog-Zielinska, E. A.; Römer, W.; Lämmermann, T.; Rohrbach, A.: 100 Hz ROCS microscopy correlated with fluorescence reveals cellular dynamics on different spatiotemporal scales. Nature Communications 13, 1758 (2022)

Spohr, C.; Poggio, T.; Andrieux, G.; Schönberger, K.; Cabezas-Wallscheid, N.; Boerries, M.; Halbach, S.; Illert, A. L.; Brummer, T.: Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 36, S. 970 - 982 (2022)

Seung, H.; Wrobel, J.; Wadle, C.; Bühler, T.; Chiang, D.; Rettkowski, J.; Cabezas-Wallscheid, N.; Hechler, B.; Stachon, P.; Maier, A. et al.; Weber, C.; Wolf, D.; Duerschmied, D.; Idzko, M.; Bode, C.; von Mühlen, C. z.; Hilgendorf, I.; Heidt, T.: P2Y₁₂-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction. Basic Research in Cardiology 117, 16 (2022)