2013, Max Planck Institute of Immunobiology and Epigenetics
Jenuwein, Thomas; Lachner, Monika; Roesch, Harald
To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimeter in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, known as heterochromatin. The research group, led by Thomas Jenuwein, at the Max Planck Institute of Immunobiology and Epigenetics investigates the molecular mechanisms necessary for the formation of heterochromatin. In particular, their research focuses on histone methylation.