Research report 2020 - Max Planck Institute of Immunobiology and Epigenetics
What makes neurons unique: gene-regulatory mechanisms that dictate the identity and function of neurons
Labor Valéry Hilgers
SummaryNeurons, also known as nerve cells, send and receive signals in our brain. They are particularly complex and fulfill functions that are unique to this cell type. Our research has shown that particular RNA sequences are of crucial importance for neurons to maintain their identity, and to develop and function properly. We study the gene-regulatory mechanisms that underlie the neuron-specific RNA landscape that drives neural function in health and disease.