Nuclei of female cells. The Xist molecules, which are responsible for the inactivation of the second X chromosome, are marked with a red dye. Copyright: MPI for Molecular Genetics / Verena Mutzel

Genetics

Illustration of nuclear analysis using confocal imaging, segmentation, and ploidy determination. Visualization includes frequency chart and spatial ploidy mapping.

A nes tool uncovers spatial patterns of DNA content across tissues more

Illustration of bacteriophages interacting with bacteria, showing DNA structures within the bacterial cells.

Bacteria borrow viruses to spread their own defences more

Brain with red dots of light, surrounded by DNA helices in darkness.

Gene defect causes developmental disorder and dementia more

Image of two rats, one female and one male, flanking heatmaps with color gradients from red to blue, indicating data variations.

Human organs form a mosaic of sex-specific characteristics  more

Reed beetle Donacia marginata on the leaf of a cattail.

The symbionts of reed beetles can adapt their gene activity flexibly to the developmental stages and ambient temperatures of their hosts more

A stylized double helix of DNA is surrounded by corn plants, while small red tractors drive on the DNA, symbolizing agricultural technology.

Regulatory DNA segments are crucial for the development of climate-resilient plant varieties more

Mtskheta, the ancient capital of the Iberian Kingdom.

Archaeogenetic study reveals this region’s population history in unprecedented detail, generating a DNA transect spanning nearly 5,000 years more

Cluster of pink flowers with green stems and leaves in a greenhouse, blurred background.

Repair of double-strand breaks in nuclear DNA provides effective protection against the integration of foreign DNA from chloroplasts more

New method for predicting plant traits for higher yields

New approach improves the prediction accuracy of agronomically relevant traits more

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Brain with red dots of light, surrounded by DNA helices in darkness.

Gene defect causes developmental disorder and dementia more

Image of two rats, one female and one male, flanking heatmaps with color gradients from red to blue, indicating data variations.

Human organs form a mosaic of sex-specific characteristics  more

A mouse oocyte extrudes a polar body.

A woman's egg cells are already formed in her body before she is born. However, with increasing age, DNA damage accumulates in the cells. Researchers have revealed why the cell’s own repair mechanisms do not fix this damage more

Multicolored rectangles arranged in a dynamic circular pattern, creating a sense of movement.

Start-up will fine-tune AI models for diagnostics and biomarker discovery more

Beethoven with a DNA strand in the background

An analysis of the famous composer's genetic make-up has revealed that DNA data has so far been too imprecise in capturing a person's abilities more

UV in the sunlight not only damages our DNA but also our RNA. After cell division, the DHX9 proteins from the mother cells assemble into stress granules to sequester the damaged RNA and shield the daughter cells

Stress granules protect cells from the effects of UV radiation more

Two young baboons in a grassy area, facing opposite directions.

Study shows multiple pathways connect early life adversity to later life health more

Hard to drug

Protein droplets reveal new ways to inhibit transcription factors in an aggressive form of prostate cancer more

Order for brewer`s yeast

An artificial chromosome combines all t-RNA genes for cellular protein production more

Increased efficiency, precision and reliability in DNA editing

New method brings breakthrough in the precise introduction of mutations in human genomes more

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Decoding gene transcription is a team effort: Patrick Cramer (centre) with members of his laboratory.

Nothing works with incomprehensible code – not even a cell. Patrick Cramer is carrying out research on the enzyme that transcribes the DNA code to enable a protein to be synthesized from a gene. To do so, he relies on high-resolution microscopes and artificial intelligence. more

Scientific highlights 2022

Scientific highlights 2022

December 14, 2022

Many publications by Max Planck scientists in 2022 were of great social relevance or met with a great media response. We have selected 12 articles to present you with an overview of some noteworthy research of the year more

Genes as parasites

Scientists analyse, how jumping genes can be copied in the DNA more

A new genome for regeneration research

First complete genome assembly of planarian flatworm reveals treasure trove on the function and evolution of genes more

Decoding the Axolotl genome

The sequencing of the largest genome to date lays the foundation for novel insights into tissue regeneration more

Possible cause of early colonial-era Mexican epidemic identified

Salmonella enterica, the bacterium responsible for enteric fever, may be the long-debated cause of the 1545-1550 AD “cocoliztli” epidemic in Oaxaca, Mexico that heavily affected the native population. more

Researchers sequence a new Neandertal genome

The genome of a European Neandertal allows more Neandertal DNA to be identified in present-day people more

How easily we tan is influenced by Neandertal DNA

Neandertal DNA influences variation in skin tone and hair colour in people living today more

First large-scale ancient genomes study from sub-Saharan African skeletons lifts veil on prehistoric populations

Genetic analyses uncover lost human populations and surprising relationships, revealing a complex history of population movements in ancient Africa more

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