Ernst-Strüngmann-Institut der Max-Planck-Gesellschaft

Ernst-Strüngmann-Institut der Max-Planck-Gesellschaft

The Ernst-Strüngmann-Institut der Max-Planck-Gesellschaft (until the end of 2025: Ernst Strüngmann Institute (ESI) for Neuroscience) performs medical scientific projects mainly in the field of cognitive brain research. The Institute’s scientists research the principles behind the communication and interaction between the billions of cells in the brain, how the particular dynamics of the brain arise in the process, and how these interactions ultimately shape human behaviour.

Contact

Deutschordenstr. 46
60528 Frankfurt am Main
Phone: +49 69 96769-501
Fax: +49 69 96769-555

PhD opportunities

This institute has no International Max Planck Research School (IMPRS).

There is always the possibility to do a PhD. Please contact the directors or research group leaders at the Institute.

A speaker in formal attire is wearing a gold chain of office and gesticulating whilst delivering a speech at a lectern in front of an illuminated emblem.

The highlights of the 2026 Annual Meeting were the presentation of the Max Planck Startup Award and Otto Hahn Medals, and an expert panel discussion on the future of democracy

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An abstract puzzle piece with red and blue lines on a green background, surrounded by other puzzle pieces.

Nonlinear units act as switches that switch between different linear processing modes depending on the context

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Boxer with exposed brain and diagram visualizing scaling-free anticipation and reaction over a time axis of 0 to 3 seconds.

If an event is more likely to occur at a certain point in time, the brain tracks the time until it occurs more precisely 

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Diagram of an experimental setup with a dome comprising a projector, mirrors, cameras and a reward system to test sensory reactions.

A new study by researchers at the Ernst Strüngmann Institute in Frankfurt suggests that cognitive states such as motivation and focus can be identified from facial expressions, even across species

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New insights into neural waves could revolutionize the development of energy-efficient AI systems

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Rechnen mit Oszillationen und Wellen: Von der Dynamik der Großhirnrinde zu analoger KI

2025  Effenberger, Felix; Singer, Wolf  

Medicine Neurosciences

We perform simulations of recurrent networks inspired by the mammalian cerebral cortex and discovered that our harmonic oscillator recurrent network (HORN) model captures essential properties of its dynamics, revealing a novel computational strategy that exploits synchrony, resonance, phase shifts and interference of traveling waves for fast, highly parallel computations. We implemented the HORN principle in analog electronic hardware, showing that it is a powerful computational substrate while at the same time being robust and highly energy efficient.

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Mapping of the entorhinal-hippocampal neuronal network

2024 Schmidt, Helene

Medicine Neurosciences

The representation of space in the brain has been studied for decades. Our team at the Ernst Strüngmann Institute (ESI) aims to fully resolve the underlying neuronal network on a cellular level. To achieve this, we use state-of-the-art 3D Electron Microscopy and AI-based analysis technology. Since these techniques are limited in volume, we mainly focus on the brain of the Etruscan shrew, the smallest terrestrial mammal. This will enable us, for the first time, to test long-standing hypotheses about the setup of the navigational system in mammalian brains.  

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Different hardware, similar outcome – naturalistic behavior in primates and rodents compared

2022 Havenith, Martha Nari; Schölvinck, Marieke

Medicine Neurosciences

How does neuronal activity represent complementary cognitive processes simultaneously at any given moment? Different animal species have used different strategies to solve this neural processing challenge – are they evolutionarily conserved or species-specific? To study these questions, our lab conducts parallel experiments in the two most dominant model species of systems neuroscience: monkeys and mice. We examine visually guided decision-making and responses of these animals in a natural context.

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A new look at coherence

2021 Hempel, Katharina; Schneider, Marius; Vinck, Martin

Medicine Neurosciences

Is coherence between brain areas a mechanism for communication, or is it a byproduct of inter-areal connectivity and oscillatory power? At the Ernst Strüngmann Institute (ESI) for Neuroscience we added new experiments, developed and tested a model how inter-areal coherence results from communication, based on inter-areal connectivity and oscillatory power.

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How does the brain process repetitions?

2020 Peter, Alina; Stauch, Benjamin J.; Fries, P.

Medicine Neurosciences

Our perception of the world relies on the coordinated activity of many billions of neurons in the brain. We at the Ernst Strüngmann Institute (ESI) have found evidence for a processing strategy of the brain that uses repeated encounters with a visual stimulus to respond more efficiently in a short time. Detailed knowledge of this mechanism could open up ways to use these abilities for medical therapies in the future.

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