Parkinson's disease involves degeneration of the olfactory system

Scientists discover anatomical link for the loss of smell in Parkinson’s disease

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Mice can smell oxygen

Mice can sense oxygen levels in the environment using specialized neurons in their noses that are present in the olfactory mucosa

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Molecular neurogenetics of the mouse olfactory system

2016 Mombaerts, Peter

Cell Biology Genetics Medicine Neurosciences

In the mouse a repertoire of ~1100 odorant receptor genes has evolved to detect a very wide variety of chemical structures in the external environment. The team of Peter Mombaerts is pursuing a genetic approach to understand the mechanisms of odorant receptor gene choice and of axonal wiring in the mouse olfactory system. A novel type of chemosensory neurons has been discovered that do not express odorant receptor genes and appear to have a specialized chemosensory function.

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