Institute

Max Planck Institute  for Heart and Lung Research

Research publications

You can find more research publications messages on the website of the Institute:
http://www.mpi-hlr.de

Research publications 2017
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Pulmonary fibrosis caused by single transcription factor

December 21, 2017

Reduced FoxO3 activity reprograms connective tissue cells, triggering the disease [more]

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Lung cancer triggers pulmonary hypertension

November 17, 2017

Nearly half of all advanced-stage lung cancer patients develop arterial pulmonary hypertension [more]

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Cancer diagnosis with a breath test

April 18, 2017

A new test for the early detection of lung cancer measures tiny changes in the composition of the breath [more]

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Oestrogen receptor causes weight loss in male mice

April 12, 2017

The receptor increases energy consumption by muscle cells and prompts weight loss [more]

Research publications 2016

Sensor for blood flow discovered in blood vessels

November 03, 2016

The PIEZO1 cation channel translates mechanical stimulus into a molecular response to control the diameter of blood vessels [more]

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Loophole for cancer cells

August 08, 2016

Cancer cells kill blood vessel cells so that they can slip through the vascular wall and form metastases [more]

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No blood vessels without cloche

July 15, 2016

After 20 years of searching scientists discover the mystic gene controlling vessel and blood cell growth in the embryo [more]

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Absence of transcription factor unleashes blood vessel growth

January 15, 2016

Max Planck scientists discover new switch for blood vessel formation [more]

Research publications 2015
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New receptor for controlling blood pressure discovered

July 23, 2015

P2Y2 receptor in blood vessel cells is a key element in the chain of regulation [more]

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Gene knockout: loss of a gene can be compensated by another gene

July 21, 2015

Effects of genome interventions depend on the methods used [more]

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Gene controls stem cells during muscle regeneration

June 01, 2015

Prmt5 gene regulates activity and function of muscle stem cells in injured skeletal muscles [more]

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Renal failure: location signals for cell division

April 24, 2015

Researchers identify molecules that help cells to pinpoint their position

[more]

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Gene regulates healing process after myocardial infarction

March 25, 2015

Reg3beta controls wound-healing process in the myocardium by attracting immune cells to the infarct tissue [more]

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Acetic acid inhibits insulin secretion

February 10, 2015

Acetate receptor inhibitors could improve diabetes therapy [more]

Research publications 2014
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New blood stem cells thanks to interferon gamma

December 29, 2014

Signal molecule gives rise to new blood stem cells in embryos [more]

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Lack of transcription factor FoxO1 triggers pulmonary hypertension

October 27, 2014

Max Planck researchers discover a new therapeutic approach [more]

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A fattening gene

April 28, 2014

Max Planck researchers discover a gene that controls fat metabolism [more]

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Mode of action of new multiple sclerosis drug discovered

April 01, 2014

Dimethyl fumarate inhibits inflammatory cell infiltration of the central nervous system through blockade of a specific receptor [more]

Research publications 2013
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The heart’s own stem cells play their part in regeneration

November 28, 2013

Sca1 stem cells replace steadily ageing heart muscle cells

[more]

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New muscle power from the lab

August 16, 2013

Pax7 stimulates powers of self-healing in muscles with the help of satellite cells [more]

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Cells make costume changes for cardiac regeneration

July 10, 2013

Atrium repairs ventricle [more]

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Gateway for metastases

July 03, 2013

Activated blood platelets enable cancer cells to penetrate blood vessels [more]

Pathological thickening of the cardiac wall halted

March 26, 2013

Inhibition of RhoGEF12 leads to considerable improvement in disease progression [more]

Research publications 2012
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G proteins regulate remodelling of blood vessels

November 13, 2012

Max Planck researchers are investigating the signalling pathways via which the smooth muscle cells of blood vessels react to extracellular changes [more]

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Finished heart switches stem cells off

July 12, 2012

Transcription factor Ajuba regulates stem cell activity in the heart during embryonic development [more]

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G protein-coupled receptor mediates the action of castor oil

May 21, 2012

Action mechanism of one of the oldest drugs known to man elucidated [more]

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Scientists aim to starve lung tumours

May 04, 2012

Enzyme regulates the division of tumour cells and blood vessel growth in the cancer tissue [more]

Researchers discover possible approach to the treatment of aggressive breast cancer

March 06, 2012

Blocking of receptor protein prevents the development of breast cancer metastases in mice [more]

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Heart of silk

January 27, 2012

Max Planck scientists use silk from the tasar silkworm as a scaffold for heart tissue [more]

Research publications 2011
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Genetic defect disturbs salt handling and pushes up blood pressure levels

November 25, 2011

Scientists from Max Planck identify gene responsible for hypertension [more]

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Diseased hearts to heal themselves in future

November 11, 2011

Oncostatin M regulates the reversion of heart muscle cells into precursor cells and is vitally important for the self-healing powers of the heart [more]

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When the lungs come under pressure

May 05, 2011

Max Planck scientists find a way of treating pulmonary arterial hypertension [more]

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Nicotinic acid blocks immune cells in atherosclerosis

February 07, 2011

New findings suggest that nicotinic acid not only alters cholesterol levels, but also has a direct anti-inflammatory effect on atherosclerotic vascular walls [more]

Research publications 2010
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Preventing heart problems while keeping a cool head

July 26, 2010

Max Planck researchers explain the cause of the flushing effect arising from cholesterol treatment with nicotinic acid [more]

Research publications 2006
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Newts which Regrow their Hearts

December 05, 2006

Max Planck scientists reveal the molecular details of regeneration in newts [more]

Research publications 2005
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Forgotten by evolution?

November 02, 2005

Max Planck scientists show that adult stem cells are possibly just the remnants of evolution [more]

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Tissue Regeneration Operates Differently Than Expected

August 01, 2005

Max Planck researchers in Bad Nauheim discover the mechanism by which adult stem cells are integrated into skeletal or heart muscle tissue [more]

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