Research report 2022 - Max Planck Institute for Heart and Lung Research

Anything beyond your DNA sequence matters 

Gu, Lei
CPI Forschungsgruppe „Epigenetik“
How do behavior and environment influence genome function? We are interested in the epigenetic regulation of complex physiological and pathological phenotypes across generations. Epigenetic changes, which include proteins, RNAs, or chemical modifications to histones, RNAs, or DNA, are reversible. They do not alter the DNA sequence. They can change the way DNA sequences are read. Our laboratory combines bioinformatics, epigenomics, tumor biology, and fly genetics to identify and study the role of epigenetic modifications and their regulatory enzymes in aging, development, and disease.

For the full text, see the German version.

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