Born on July 21, 1956 in Gelnhausen. Study of human medicine, doctorate Frankfurt Univ. (1982), German Habilitation in biological chemistry Frankfurt Univ. (1988), member of Scientific Staff Laboratory of Molecular Biology, Cambridge (1989-1991), Professor Freiburg Univ. (1991-1994), Full Professor Heidelberg Univ./German Cancer Research Centre (1994-1997), Director and Scientific Member at the Max Planck Institute of Immunobiology and Epigenetics (since 1998).