Contact

Florian Frisch
Press Officer
Phone:+49 351 210-2840Fax:+49 351 210-1019
Prof. Dr. Eugene W. Myers
Prof. Dr. Eugene W. Myers
Phone:+49 351 210-1220

Related links

Video

Virtual blood flow

Ivo Sbalzarini, one of the heads of the Center, is examining the cardiovascular system of a zebrafish in the 3D Cave of the Center for System Biology in Dresden.

Further articles

Eugene W. Myers never attended a biology course. Despite this fact, he has made a career for himself in this field, and in developing a computer program, made a major contribution to decoding the human genome. He recently was appointed as Director at the the Max Planck Institute for Molecular Cell Biology and Genetics, and the Klaus-Tschira Chair of the Systems Biology Center in Dresden.

Source of life

May 22, 2017

Eugene W. Myers never attended a biology course. Despite this fact, he has made a career for himself in this field, and in developing a computer program, made a major contribution to decoding the human genome. He recently was appointed as Director at the the Max Planck Institute for Molecular Cell Biology and Genetics, and the Klaus-Tschira Chair of the Systems Biology Center in Dresden. [more]

Opening

Center for Systems Biology Dresden (CSBD) has opened

Researchers from different disciplines will jointly examine cell processes at the new facility

May 29, 2017

The Minister President of the Free State of Saxony, Stanislaw Tillich, as well as the President of the Max Planck Society, Martin Stratmann were among the speakers at the inauguration on May 31. The new centre is an initiative of several institutions: the Max Planck Institute of Molecular Cell Biology and Genetics, the Max Planck Institute for the Physics of Complex Systems, as well as the Technische Universität Dresden. Construction costs were funded by the Free State of Saxony, the German Federal Ministry of Education and Research, as well as the Klaus Tschira Stiftung GmbH. Craig Venter, American biochemist and entrepreneur, whose company Celera Corporation was the first to sequence the entire human genome, will be the guest of honour at the opening ceremonies on June 1.
The Center for System Biology Dresden. The building was designed by the architects Heikkinen-Komonen and cost around 26 million euros. Zoom Image
The Center for System Biology Dresden. The building was designed by the architects Heikkinen-Komonen and cost around 26 million euros.

Systems biology involves a sensitive equilibrium: molecules organise themselves into cells, cells intertwine with one another to become tissue, organs in turn are formed from tissue. This only functions in the context of a correct spatial arrangement and temporal sequence. The focus of the researchers at the Center for Systems Biology Dresden is to understand how cells coordinate with each other, in order to form tissue of a certain shape, size and function.

In their quest to yet better understand these processes, computer scientists, physicists, engineers and mathematicians in Dresden will be developing new microscopes and automated methods of image analysis. This will enable them to more effectively evaluate image data from their experiments and thereby obtain information on the organisation of molecules and their interaction. The scientists will also create biophysical models for the data and then develop these models further so that computer simulations of life processes can be produced. The centre has, among other resources, optics areas for tailored microscopy, as well as an area for the projection of virtual reality.

A focus on the overall picture

Self-driving microcopse: The light-sheet microscope developed by Gene Myers's working group can ‘drive’ itself automatically by adapting to the challenging and dynamic optical conditions of large living specimens. In a light-sheet microscope, a laser light sheet illuminates the sample perpendicularly to the observation along a thin plane within the sample. Out-of-focus and scattered light from other planes - which often impair image quality - is largely avoided because only the observed plane is illuminated. This smart autonomous microscope can in real-time analyse and optimize the spatial relationship between light-sheets and detection planes across the specimen volume. This enables the creation of images in previously unprecedented quality. Zoom Image
Self-driving microcopse: The light-sheet microscope developed by Gene Myers's working group can ‘drive’ itself automatically by adapting to the challenging and dynamic optical conditions of large living specimens. In a light-sheet microscope, a laser light sheet illuminates the sample perpendicularly to the observation along a thin plane within the sample. Out-of-focus and scattered light from other planes - which often impair image quality - is largely avoided because only the observed plane is illuminated. This smart autonomous microscope can in real-time analyse and optimize the spatial relationship between light-sheets and detection planes across the specimen volume. This enables the creation of images in previously unprecedented quality. [less]

The new building brings theoreticians and practitioners together in one place. “The Center for Systems Biology constitutes a crucial building block for the future of life sciences in Dresden. The founding director Gene Myers is heading up a team of researchers who are following an approach through which the development process of biological systems can be digitally captured in an unprecedented manner. This gives the centre its world class status, thereby strengthening the research environment of Dresden as a whole,” said Max Planck President Stratmann.

After construction has been completed, around 120 scientists will be conducting research at the Center for Systems Biology. The centre will be headed up by the Max Planck Directors Gene Myers und Frank Jülicher, as well as Ivo Sbalzarini from the Technische Universität Dresden. They will work closely with four junior scientist groups focusing on the following areas of specialization: biochemical networks (Christoph Zechner), structural networks (Carl Modes), comparative genomics (Michael Hiller) and bioimage informatics (Florian Jug).

 
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