Born on December 11, 1968 in Juvisy-sur-Orge, France. Study of biology, microbiology, biochemistry and genetics at the University Pierre and Marie Curie (UPMC), Paris (1986-1992). Graduate student at Institut Pasteur (1992-1995) and University Teaching Assistant at UPMC, Paris (1993-1995). Post-Doc at Institut Pasteur (1995-1996) and at The Rockefeller University, New York (1996-1997). Assistant Research Scientist at New York University Medical Center (1997-1999). Research Associate at the St. Jude Children's Research Hospital (1999) and at the Skirball Institue of Biomolecular Medicine, New York (1999-2002).
Lab Head and Guest Professor at the Institute of Microbiology and Genetics (2002-2004), Vienna University. Lab Head, Assistant Professor at the Department of Microbiology and Immunobiology (2004-2006). Private Docent (Microbiology) and Habilitation, Centre of Molecular Biology (2006). Lab Head and Associate Professor at the Max F. Perutz Laboratories (2006-2009).
Lab Head, Associate Professor at the Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University (2009-2014) and since 2014 Lab Head as Visiting Professor. Docent (Medical Microbiology), Umeå University (2013). Department Head and W3 Professor at the Helmholtz Centre for Infection Research, Braunschweig and the Hannover Medical School (2013-2015). Since 2014, Alexander von Humboldt Professor. Since 2015, Director at the Max Planck Institute for Infection Biology. Since 2016, Honorary Professor at Humboldt University in Berlin.