Research report 2021 - Max Planck Institute of Molecular Physiology

Anti-aging for the cytoskeleton with therapeutic potential

Pospich, Sabrina.; Raunser, Stefan
Abteilung „Structural Biochemistry“
Whether antibiotics, cholesterol-lowering agents or fluorescent proteins: natural substances, for example from fungi and marine organisms, have always been used in medicine and science. Applying high-resolution cryo-electron microscopy, we have now been able to elucidate for the first time how two natural toxins influence the structure of actin filaments and thus the regulation of the cytoskeleton. While these toxins are already of great use for research, one day they could be used to specifically agglutinate the cytoskeleton of cancer cells and thus kill them.

For the full text, see the German version.

Go to Editor View