Research report 2020 - Max Planck Institute for Molecular Biomedicine

The sleeping embryo

Bedzhov, Ivan
Forschungsgruppe "Embryonic Self-Organization"
Early stages of mammalian embryos are able to enter a naturally occurring dormant state (diapause) to slow their development during unfavorable environmental conditions. Surprisingly, we found that these seemingly “sleeping” embryos exhibit dynamic cell-cell communication and shape-shifting tissue architecture during stasis, which is required to maintain their long-term developmental potential.

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