Scientific Publications

Zempel, H.; Mandelkow, E.-M.: Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia. Molecular Neurodegeneration 10, 68 (2015)

Fechner, S.; Alvarez, L.; Bönigk, W.; Müller, A.; Berger, T.; Pascal, R.; Trötschel, C.; Poetsch, A.; Stölting, G.; Siegfried, K. R. et al.; Seifert, R.; Kaupp, U. B.: A K+-selective CNG channel orchestrates Ca2+ signalling in zebrafish sperm. eLife 4, e07624 (2015)

Royeck, M.; Kelly, T.; Opitz, T.; Otte, D.-M.; Rennhack, A.; Woitecki, A.; Pitsch, J.; Becer, A.; Schoch, S.; Kaupp, U. B. et al.; Yaari, Y.; Zimmer, A.; Beck, H.: Downregulation of spermine Augments dendritic persistent sodium currents and synaptic integration after status epilepticus. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 35 (46), pp. 15240 - 15253 (2015)

Egger, R.; Schmitt, A. C.; Wallace, D. J.; Sakmann, B.; Oberlaender, M.; Kerr, J. N. D.: Robustness of sensory-evoked excitation is increased by inhibitory inputs to distal apical tuft dendrites. Proceedings of the National Academy of Sciences of the United States of America 112 (5), pp. 14072 - 14077 (2015)

Yamada, K.; Patel, T. K.; Hochgräfe, K.; Mahan, T. E.; Jiang, H.; Stewart, F. R.; Mandelkow, E.-M.; Holtzman, D. M.: Analysis of in vivo turnover of tau in a mouse model of tauopathy. Molecular Neurodegeneration 10, 55 (2015)

Börger, C.; Schünke, S.; Lecher, J.; Stoldt, M.; Winkhaus, F.; Kaupp, U. B.; Willbold, D.: Resonance assignment of the ligand-free cyclic nucleotide-binding domain from the murine ion channel HCN2. Journal of Biomolecular NMR 9 (2), pp. 243 - 246 (2015)

Lu , C.-H.; Cecconello, A.; Oi, X.-J.; Wu, N.; Jester, S.-S.; Famulok, M.; Matthies, M.; Schmidt, T.-L.; Willner, I.: Switchable Reconfiguration of a seven-ring interlocked DNA catenane nanostructure. Nano Letters 15 (10), pp. 7133 - 7137 (2015)

Kulbida, R.; Wang, Y.; Mandelkow, E.-M.; Schoch, S.; Becker, A. J.; van Loo, K. M. J.: Molecular imaging reveals epileptogenic Ca2+-channel promoter activation in hippocampi of living mice. Brain Structure & Function 220 (5), pp. 3067 - 3073 (2015)

Pickardt, M.; Neumann, T.; Schwizer, D.; Callaway, K.; Vendruscolo, M.; Schenk, D.; George-Hyslop, P. S.; Mandelkow, E.-M.; Dobson, C. M.; McConlogue, L. et al.; Mandelkow, E.; Toth, G.: Identification of small molecule inhibitors of tau aggregation by targeting monomeric tau as a potential therapeutic approach for tauopathies. Current Alzheimer Research 12 (9), pp. 814 - 828 (2015)

Herzog, H.; Steltenkamp, S.; Klein, A.; Tätzner, S.; Schulze, E.; Bleckmann, H.: Micro-machined flow sensors mimicking lateral line canal neuromasts. Micromachines 6 (8), pp. 1189 - 1212 (2015)

Jikeli, J.; Alvarez, L.; Friedrich, B. M.; Wilson, L. G.; Pascal, R.; Colin, R.; Pichlo, M.; Rennhack, A.; Brenker, C.; Kaupp, U. B.: Sperm navigation along helical paths in 3D chemoattractant landscapes. Nature Communications 6, 7985 (2015)

Schröder, B.; Weber, T.; Yalunin, S. V.; Kiel, T.; Matyssek, C.; Sivis, M.; Schäfter, S.; Cube, F. v.; Irsen, S.; Busch, K. et al.; Roper, C.; Linden, S.: Real-space imaging of nanotip plasmons using electron energy loss spectroscopy. Physical Review B 92 (8), 085411 (2015)

Scheib, U.; Stehfest, K.; Gee, C. E.; Körschen, H. G.; Fundim, R.; Oertner, T. G.; Hegemann, P.: The rhodopsin–guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling. Science Signaling 8 (389), rs8 (2015)

Schroeder, B.; Weber, T.; Yalunin, S. V.; Kiel, T.; Matyssek, C.; Sivis, M.; Schaefer, S.; von Cube, F.; Irsen, S.; Busch, K. et al.; Ropers, C.; Linden, S.: Real-space imaging of nanotip plasmons using electron energy loss spectroscopy. Physical Review B 92 (8), 085411 (2015)

Schwalbe, M.; Kadavath, H.; Biernat, J.; Ozenne, V.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Structural impact of tau phosphorylation at threonine 231. Structure 23 (8), pp. 1448 - 1458 (2015)

Kadavath, H.; Jaremko, M.; Jaremko, L.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Folding of the Tau Protein on microtubules. Angewandte Chemie, International Edition in English 54 (35), pp. 10347 - 10351 (2015)

Mangino, G.; Famiglietti, M.; Capone, C.; Veroni, C.; Percario, Z. A.; Leone, S.; Fiorucci, G.; Lüf, S.; Romeo, G.; Agresti, C. et al.; Persichini, T.; Geyer, M.; Affabris, E.: HIV-1 myristoylated nef treatment of murine microglial cells activates inducible nitric oxide synthase, NO2 production and neurotoxic activity. PLoS One 10 (6), e0130189 (2015)

Kühn, S.; Erdmann, C.; Block, J.; Schwenkmezger, L.; Steffen, A.; Rottner, K.; Geyer, M.: The structure of FMNL2–Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation. Nature Communications 6, 7088 (2015)

Kadavath, H.; Hofele, R. V.; Biernat, J.; Kumar, S.; Tepper, K.; Urlaub, H.; Mandelkow, E.; Zweckstetter, M.: Tau stabilizes microtubules by binding at the interface between tubulin heterodimers. Proceedings of the National Academy of Sciences of the United States of America 112 (24), pp. 7501 - 7506 (2015)

Shammas , S. L.; Garcia, G. A.; Kumar, S.; Kjaergaard, M.; Horrocks, M. H.; Shivji, N.; Mandelkow, E.-M.; Knowles, T. P. J.; Mandelkow, E.; Klenerman, D.: A mechanistic model of tau amyloid aggregation based on direct observation of oligomers. Nature Communications 6, 7025 (2015)