Scientific Publications

Guo, J.; Otis, J. M.; Suciu, S. K.; Catalano, C.; Xing, L.; Constable, S.; Wachten, D.; Gupton, S.; Lee, J.; Lee, A. et al.; Blackley, K. H.; Ptacek, T.; Simon, J. M.; Schurmans, S.; Stuber, G. D.; Caspary, T.; Anton, E.S.: Primary cilia signaling promotes axonal tract development and is disrupted in Joubert Syndrome-related disorder models. Developmental Cell 51 (6), e5, pp. 759 - 774 (2019)

Pellkofer, H.; Ihler, F.; Weiss, B. G.; Trothe, J.; Kadavath, H.; Chongtham, M.; Kunadt, M.; Riedel, D.; Lornsen, F.; Wilken, P. et al.; Bartels, C.; Hirschel, S.; Russo, S. G.; Stransky, E.; Trojan, L.; Schmidt, B.; Mandelkow, E.; Zweckstetter, M.; Canis, M.; Schneider, A.: Evaluation of the methoxy-X04 derivative BSC4090 for diagnosis of prodromal and early Alzheimer's disease from bioptic olfactory mucosa. European Archives of Psychiatry and Clinical Neuroscience 269 (8), pp. 973 - 984 (2019)

Klausen, C.; Kaiser, F.; Stüven, B.; Hansen, J. N.; Wachten, D.: Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors. Biochemical Society Transactions 47 (6), pp. 1733 - 1747 (2019)

Vishniakou, I.; Plöger, P. G.; Seelig, J. D.: Virtual reality for animal navigation with camera-based optical flow tracking. Journal of Neuroscience Methods 327, 108403 (2019)

Marquart, G. D.; Tabor, K. M.; Bergeron, S. A.; Briggman, K. L.; Burgess, H. A.: Prepontine non-giant neurons drive flexible escape behavior in zebrafish. PLoS Biology 17 (10), e3000480 (2019)

Matsumoto, A.; Briggman, K. L.; Yonehara, K.: Spatiotemporally asymmetric excitation supports mammalian retinal motion sensitivity. Current Biology 29 (19), pp. 3277 - 3288 (2019)

Valero, J.; Centola, M.; Yinzhou, M.; Skugor, M.; Yu, Z.; Haydell, M. W.; Keppner, D.; Famulok, M.: Design, assembly, characterization, and operation of double-stranded interlocked DNA nanostructures. Nature Protocols 14 (10), pp. 2818 - 2855 (2019)

Molina-Obando, S.; Vargas-Fique, J. F.; Henning, M.; Gur, B.; Schladt, T. M.; Akhtar, J.; Berger, T. K.; Silies, M.: ON selectivity in Drosophila vision is a multisynaptic process involving both glutamatergic and GABAergic inhibition. eLife 8, e49373 (2019)

Stabel, R.; Stüven, B.; Hansen, J. N.; Körschen, H. G.; Wachten, D.; Möglich, A.: Revisiting and redesigning light-activated cyclic-mononucleotide phosphodiesterases. Journal of Molecular Biology (London) 431 (17), pp. 3029 - 3045 (2019)

Ukmar-Godec, T.; Hutten, S.; Grieshop, M. P.; Rezaei-Ghaleh, N.; Cima-Omori, M.-S.; Biernat, J.; Mandelkow, E.; Soeding, J.; Dormann, D.; Zweckstetter, M.: Lysine/RNA-interactions drive and regulate biomolecular condensation. Nature Communications 10, 2909 (2019)

Raju, D. N.; Hansen, J. N.; Rassmann, S.; Stüven, B.; Jikeli, J. F.; Strünker, T.; Körschen, H. G.; Möglich, A.; Wachten, D.: Cyclic nucleotide-specific optogenetics highlights compartmentalization of the sperm flagellum into cAMP microdomains. Cells 8 (7), 648 (2019)

Huang, X.; Rangel, M.; Briggman, K. L.; Wei, W.: Neural mechanisms of contextual modulation in the retinal direction selective circuit. Nature Communications 10, 2431 (2019)

Ambadipudi, S.; Reddy, J. G.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau. Chemical Science 10 (26), pp. 6503 - 6507 (2019)

Skugor, M.; Valero, J.; Murayama, K.; Centola, M.; Asanuma, H.; Famulok, M.: Orthogonally photocontrolled non-autonomous DNA walker. Angewandte Chemie International Edition in English 58 (21), pp. 6948 - 6951 (2019)

Butler, V. J.; Salazar, D. A.; Soriano-Castell, D.; Alves-Ferreira, M.; Dennissen, F. J. A.; Vohra, M.; Oses-Prieto, J. A.; Li, K. H.; Wang, A. L.; Jing, B. et al.; Li, B.; Groisman, A.; Gutierrez, E.; Mooney, S.; Burlingame, A. L.; Ashrafi, K.; Mandelkow, E.-M.; Encalada, S. E.; Kao, A. W.: Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport. Human Molecular Genetics 28 (9), pp. 1498 - 1514 (2019)

Pir, G. J.; Choudhary, B.; Kaniyappan, S.; Chandupatla, R. R.; Mandelkow, E.; Mandelkow, E.-M.; Wang, Y.: Suppressing Tau Aggregation and Toxicity by an Anti-Aggregant Tau Fragment. Molecular Neurobiology 56 (5), pp. 3751 - 3767 (2019)

Sherpa, R. T.; Mohieldin, A. M.; Pala, R.; Wachten, D.; Ostrom, R. S.; Nauli, S. M.: Sensory primary cilium is a responsive cAMP microdomain in renal epithelia. Scientific Reports 9, 6523 (2019)

Seelig, J. D.; Flores Valle, A.: Two-photon Bessel beam tomography for fast volume imaging. Optics Express 27 (9), pp. 12147 - 12162 (2019)

Praemassing, M.; Leuteritz, T.; Schill, H. J.; Fassbender, A.; Irsen, S.; Linden, S.: Freestanding metasurfaces for optical frequencies. Optics Letters 44 (8), pp. 2105 - 2108 (2019)

Pickhardt, M.; Tassoni, M.; Denner, P.; Kurkowsky, B.; Kitanovic, A.; Moehl, C.; Fava, E.; Mandelkow, E.: Screening of a neuronal cell model of tau pathology for therapeutic compounds. Neurobiology of Aging 76, pp. 24 - 34 (2019)