Born 1958 in Triest (Italy). Study of biochemistry, doctorate Triest Univ. (1982), group head at the European Molecular Biology Laboratory (EMBL) Heidelberg in the cell biology programme (1991), Director and Scientific Member at the Max Planck Institute of Molecular Cell Biology and Genetics (since 1998). Awarded the Gottfried Wilhelm Leibniz Prize in 2006. In 2019 he became elected Member of the Istituto Veneto di Scienze, Lettere ed Arti.