Research report 2022 - Max Planck Institute of Molecular Cell Biology and Genetics
Quantitative lipid biochemistry in living cells
Max-Planck-Institut für molekulare Zellbiologie und Genetik
SummaryThe Nadler lab develops chemical probes that can be used to study the function of lipids or fats in cell biology. Using these tools, they are now able to address a number of fundamental questions in membrane biology: Why do biological membranes exhibit an asymmetric lipid distribution? How does the cell direct lipid molecules with extremely variable structural properties to the correct organelle membranes? How are lipids moved across membrane contact sites? How do lipids interact with proteins in cellular signaling cascades?