Research report 2021 - Max Planck Institute for Metabolism Research
Heterogeneity of satiety-promoting neurons in the brain
Authors
Biglari, Nasim.; Brüning, Jens C.
Departments
Abteilung „Neuronal Control of Metabolism“
Summary
The hypothalamus is an area in the brain that regulates metabolism. It consists of neuronal groups, one of which is the Pro-opiomelanocortin- expressing group. POMC neurons drive satiety and use of stored energy in the body. Studying this neuronal group has led us to find different subgroups within a population that was thought to be uniform. We are studying in detail how they influence metabolism.