Research report 2021 - Max Planck Institute for Biological Intelligence (Martinsried site)
To act or not to act?
Max-Planck-Forschungsgruppe „Brain-Wide Circuits of Behaviour“
SummaryDepression is a disorder that affects thoughts, but also the ability to engage in the most basic actions, as simple as getting out of bed. Therefore, this disorder must perturb a core network of brain regions implicated in our motivation to act. Our team at the Max Planck Institute of Neurobiology investigates in mice what part of the brain is active when they spontaneously engage in an action, using a novel method to record whole-brain activity. The goal is to better understand what brain circuits controls our drive to act and how they become dysfunctional in psychiatric disorders.