Research report 2020 - Max Planck Institute for Human Cognitive and Brain Sciences

What lies between grey and white in the brain

Kirilina, Evgeniya; Helbling, Saskia; Morawski, Markus; Pine, Kerrin; Reimann, Katja; Jankuhn, Steffen; Dinse, Juliane; Deistung, Andreas; Reichenbach, Jürgen R.; Trampel, Robert; Geyer, Stefan; Müller, Larissa; Jakubowski, Norbert; Arendt, Thomas; Bazin, Pierre-Louis; Weiskopf, Nikolaus
Abteilung Neurophysik, Max-Planck-Institut für Kognitions- und Neurowissenschaften
Superficial white matter (SWM), a less than 1 mm thick interface between grey and white matter, contains most cortico-cortical white matter connections encompassing the short U-fibers. We developed an advanced neuroimaging method for SWM mapping in living individuals. Thereby we were able to show that the SWM contains significant amounts of iron. It is assumed that this iron is required for the myelination of the U-fibres. Our SWM mapping approach paves for systematic studies in the inter-individual differences, brain plasticity and pathologies in the human brain.

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