Research report 2018 - Max Planck Institute for Biological Cybernetics
Neurochemical response patterns to neuropsychiatric drugs
Noori, Hamid R.
Physiologie kognitiver Prozesse / Neuronale Konvergenz
SummaryNeuropsychiatric conditions are disorders originating in the nervous system. The past 50 years show a steady increase in neurochemical studies on rodent brain. Thereby, neuroscientists have joined the big-data club that was traditionally reserved for astronomers and physicists. By systematically analyzing data from thousands of studies, we were able to develop a free database for optimizing further research. We also demonstrated a mismatch between the current classification of neuropsychiatric drugs and spatiotemporal neurostransmitter response patterns at the systems level.