Research report 2018 - Max Planck Institute for Biophysical Chemistry
A switch for human genes
SummaryGenes must be activated to make use of the genetic information in living cells. Gene activation starts with transcription, which produces RNA copies of genes. Recent studies now reveal a switch for transcription that regulates the activity of the enzyme RNA polymerase II at the beginning of genes. These results could only intriguingly be obtained by combining different experimental and computational techniques.