Research report 2004 - Max Planck Institute for Metabolism Research

Early diagnosis of Neurodegenerative Diseases to Prevent Dementia

Herholz, Karl & Heiss. Wolf-Dieter

Allgemeine Neurologie (Prof. Dr. Wolf-Dieter Heiss)
MPI für neurologische Forschung, Köln

Prevention of dementia by early diagnosis of neurodegenerative disease, in particular Alzheimer’s disease, and efficient testing of neuroprotective drugs is an important goal in all industrialized countries because of the prolongation of life span. With positron emission tomography (PET) we can identify a high-risk group of non-demented patients with mild cognitive impairment who have a very high likelihood to progress to dementia within 1-2 years. With this technique, one can also directly compare and validate animal models of neurodegenerative disease with human disease and test specific therapeutic approaches.

For the full text, see the German version.

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