Research report 2007 - Max Planck Institute of Colloids and Interfaces
Peptides at Interfaces
Brezesinski, Gerald; Möhwald, Helmuth
Grenzflächen (Prof. Dr. Helmuth Möhwald)
MPI für Kolloid- und Grenzflächenforschung, Potsdam
SummaryThe characterization of molecular mechanisms of interactions between peptides and cell membranes is very important for the understanding of structure-function relations. These are studied with 2-dimensional monolayers at fluid interfaces using modern biophysical methods. This report shows how the interface influences the secondary structure of the peptides, and vice versa how the peptide adsorption leads to changes in the structure of phospholipid layers.