Research report 2007 - Max Planck Institute for Molecular Genetics
Regulatory networks of trunk formation in mammals
Authors
Herrmann, Bernhard G.
Departments
Entwicklungsgenetik (Prof. Dr. Bernhard Herrmann)
MPI für molekulare Genetik, Berlin
Summary
Mesoderm formation is an important process of embryonic development. It plays an essential role in trunk formation and organ development in mammals. It is controlled by several interacting signalling pathways, which also play an important role in tumour progression. Novel methods are utilized for deciphering the complex regulatory networks comprising thousands of gene products, which control mesoderm formation in the embryo and in tumours.