Research report 2006 - Max Planck Institute for Informatics
Computational Epigenetics: Bioinformatics prediction for new approaches to cancer treatment
Bock, Christoph; Lengauer, Thomas
Bioinformatik und Angewandte Algorithmik (Prof. Dr., Ph. D. Thomas Lengauer)
MPI für Informatik, Saarbrücken
SummaryDamages to the DNA sequence cause only approximately half of all cancers, according to recent research. Equally important – and significantly less understood – are the epigenetic roots of cancer, which involve persistent de-regulation of the human genome. At the Max Planck Institute for Informatics the bioinformatic methods are developed for design and optimization of epigenetic cancer therapies.