Research report 2016 - Max Planck Institute for Informatics

Reconstruction of cell lineage trees

Andres, Björn1; Schiele, Bernt1; Jug, Florian2; Blasse, Corinna2, Myers, Eugene W.2
1 „Computer Vision and Multimodal Computing“, MPI für Informatik, Saarbrücken
2 „Gene Myers Group“ MPI für molekulare Zellbiologie und Genetik, Dresden
Rapid progress in light microscopy allows biologists to image the development of living tissue consisting of several thousand cells. Scientists at the Max Planck Institute for Informatics and the Max Planck Institute for Molecular Cell Biology and Genetics are jointly developing algorithms for reconstructing the lineage of all cells automatically from image data. A central aspect of their research consists in an approach by which two sub-problems are solved jointly, an image segmentation problem and a cell tracking problem. This approach has enabled accurate reconstructions of lineage trees.

For the full text, see the German version.

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