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Prof. Dr. Svante Pääbo

Max Planck Institute for Evolutionary Anthropology, Leipzig

Phone: +49 341 3550-500
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Sandra Jacob

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Max Planck Institute for Evolutionary Anthropology, Leipzig

Phone: +49 341 3550-122
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Original publication

Qiaomei Fu, Matthias Meyer, Xing Gao, Udo Stenzel, Hernán A. Burbano, Janet Kelso, Svante Pääbo
DNA analysis of an early modern human from Tianyuan Cave, China
PNAS, Online Early Edition, January 21, 2013

Related articles

Evolutionary Biology . Genetics

A relative from the Tianyuan Cave

Ancient DNA has revealed that humans living some 40,000 years ago in the area near Beijing were likely related to many present-day Asians and Native Americans

January 21, 2013

An international team of researchers including Svante Pääbo and Qiaomei Fu of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, sequenced nuclear and mitochondrial DNA that had been extracted from the leg of an early modern human from Tianyuan Cave near Beijing, China. Analyses of this individual's DNA showed that the Tianyuan human shared a common origin with the ancestors of many present-day Asians and Native Americans. In addition, the researchers found that the proportion of Neanderthal and Denisovan-DNA in this early modern human is not higher than in people living in this region nowadays.
The leg of the early modern human from Tianyuan Cave was used for the genetic analysis as well as for carbon dating. Zoom Image
The leg of the early modern human from Tianyuan Cave was used for the genetic analysis as well as for carbon dating.

Humans with morphology similar to present-day humans appear in the fossil record across Eurasia between 40,000 and 50,000 years ago. The genetic relationships between these early modern humans and present-day human populations had not yet been established. Qiaomei Fu, Matthias Meyer and colleagues of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, extracted nuclear and mitochondrial DNA from a 40,000 year old leg bone found in 2003 at the Tianyuan Cave site located outside Beijing. For their study the researchers were using new techniques that can identify ancient genetic material from an archaeological find even when large quantities of DNA from soil bacteria are present.

The researchers then reconstructed a genetic profile of the leg's owner. “This individual lived during an important evolutionary transition when early modern humans, who shared certain features with earlier forms such as Neanderthals, were replacing Neanderthals and Denisovans, who later became extinct”, says Svante Pääbo of the Max Planck Institute for Evolutionary Anthropology, who led the study.

Researchers carrying out excavation works at the Tianyuan Cave from which the leg bones had been excavated in 2003. Zoom Image
Researchers carrying out excavation works at the Tianyuan Cave from which the leg bones had been excavated in 2003.

The genetic profile reveals that this early modern human was related to the ancestors of many present-day Asians and Native Americans but had already diverged genetically from the ancestors of present-day Europeans. In addition, the Tianyuan individual did not carry a larger proportion of Neanderthal or Denisovan DNA than present-day people in the region. “More analyses of additional early modern humans across Eurasia will further refine our understanding of when and how modern humans spread across Europe and Asia”, says Svante Pääbo.

Parts of the work were carried out in a new laboratory jointly run by the Max Planck Society and the Chinese Academy of Sciences in Beijing.

PNAS/SJ/HR

 


 
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