Proteomics

After the genome, researchers are now turning their attention towards the proteome. They aim to establish a complete human protein catalogue – hoping to gain new insights into cell functions and the causes of diseases.

Cancer as a model case

November 12, 2015

Cell Biology

Hans Lehrach and his colleagues comprise one of the few research teams in the world to work on computer models that aim to reconstruct all processes in a cancer cell and a healthy cell at the same time. more

Visual proteomics – on the way to a three-dimensional protein atlas

November 10, 2015

Cell Biology

If proteins are to fulfil their functions in a cell, they need to be in the right place at the right time. In addition, they often join forces and form complexes made out of several thousand proteins. more

From genome to interactome

November 05, 2015

Cell Biology

Genome, proteome, interactome – since the beginning of the 21^st century, the life sciences have been focussing on cataloguing the cell. more

A Library of Proteins

Video December 12, 2012

Cell Biology

About 12,000 proteins are produced in typical human cells – more than 120,000 various proteins in total. Matthias Mann at the Max Planck Institute of Biochemistry in Martinsried, Germany, has set himself the target of establishing a protein library of the human body. Not an easy project - because in contrast to genes, proteins are extremely variable. In addition, many various factors influence which proteins a cell produces. Nevertheless, Mann is able to identify the proteins with mass spectrometry, nanochromatography and special computer software. more