Research report 2014 - Max Planck Institute for Infection Biology
Plasmodium infections: attacking the parasite before malaria hurts
SummaryMalaria is a poverty-related infectious disease in the tropics and a major challenge for medical research. A better molecular understanding of the underlying mechanisms of Plasmodium-host interactions and the complex parasite life cycle is the basis for innovative evidence-based intervention strategies. Novel insights from the clinically silent liver infection and related parasites in Afrotropical bats indicate previously unrecognized opportunities to stop the parasite prior to malaria onset and to induce a decisive immunological advantage in the host.