Research report 2014 - Max Planck Institute for Metabolism Research
Metabolic disorders: Nutrition during pregnancy affects offspring
Hausen, Anne Christine; Brüning, Jens C.
Neuronal Control of Metabolism
SummaryObesity, type 2 diabetes mellitus and associated dieseases are on a constant rise and not only reduce quality of life but also are putting a burden on our society. Large efforts have been put into a better understanding of the homeostatic control mechanisms involved in regulation of body weight and energy homeostasis. It is known that maternal obesity, diabetes and hyperglycemia during pregnancy results in an increased risk for the offspring to develop obesity and diabetes later in life. By performing studies in mice, scientists can gain insights into the underlying complex mechanisms.