Research report 2014 - Max Planck Institute for Heart and Lung Research

G-protein-mediated signaling cascades in the cardiovascular and immune system

Authors
Wettschureck, Nina
Departments
G-Protein-Gruppe innerhalb der Abteilung II (Pharmakologie)
Summary
Heterotrimeric G-proteins transduce signals from activated G-protein-coupled receptors to intracellular signaling cascades. Scientists at the MPI for Heart and Lung Research have a longstanding interest in the role of the families Gq/G11 and G12/G13, their upstream activators and downstream effectors, in cardiovascular and immunological functions. The long-term goal of their work is to identify new targets for the treatment of chronic cardiovascular and immune disease.

For the full text, see the German version.

Go to Editor View