Publikationen 2018


  1. Bacman, S. R.; Kauppila, J. H. K.; Pereira, C. V.; Nissanka, N.; Miranda, M.; Pinto, M.; Williams, S. L.; Larsson, N. G.; Stewart, J. B.; Moraes, C. T.: MitoTALEN reduces mutant mtDNA load and restores tRNA(Ala) levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med 24 (11), S. 1696 - 1700 (2018)
  2. Gammage, P. A.; Viscomi, C.; Simard, M. L.; Costa, A. S. H.; Gaude, E.; Powell, C. A.; Van Haute, L.; McCann, B. J.; Rebelo-Guiomar, P.; Cerutti, R. et al.; Zhang, L.; Rebar, E. J.; Zeviani, M.; Frezza, C.; Stewart, J. B.; Minczuk, M.: Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nat Med 24 (11), S. 1691 - 1695 (2018)
  3. Colby, T.; Bonfiglio, J. J.; Matic, I.: Nonlocalized Searching of HCD Data for Fast and Sensitive Identification of ADP-Ribosylated Peptides. Methods Mol Biol 1813, S. 255 - 269 (2018)
  4. Seidel, J.; Valenzano, D. R.: The role of the gut microbiome during host ageing. F1000Res 7 (2018)
  5. Dodzian, J.; Kean, S.; Seidel, J.; Valenzano, D. R.: A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri). J Vis Exp (134) (2018)
  6. Saita, S.; Tatsuta, T.; Lampe, P. A.; Konig, T.; Ohba, Y.; Langer, T.: PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. EMBO J (2018)
  7. Annibal, A.; Karalay, o.; Latza, C.; Antebi, A.*.: A novel EI-GC/MS method for the accurate quantification of anti-aging compound oleoylethanolamine in C. elegans. Analytical Methods (22) (2018)
  8. Augustin, H.; McGourty, K.; Allen, M. J.; Adcott, J.; Wong, C. T.; Boucrot, E.; Partridge, L.: Impact of insulin signaling and proteasomal activity on physiological output of a neuronal circuit in aging Drosophila melanogaster. Neurobiol Aging 66, S. 149 - 157 (2018)
  9. Bartlett, E.; Bonfiglio, J. J.; Prokhorova, E.; Colby, T.; Zobel, F.; Ahel, I.; Matic, I.: Interplay of Histone Marks with Serine ADP-Ribosylation. Cell Rep 24 (13), S. 3488 - 3502 e5 (2018)
  10. Blank, M. L.; Parker, M. L.; Ramaswamy, R.; Powell, C. J.; English, E. D.; Adomako-Ankomah, Y.; Pernas, L. F.; Workman, S. D.; Boothroyd, J. C.; Boulanger, M. J. et al.; Boyle, J. P.: A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Mol Microbiol 108 (5), S. 519 - 535 (2018)
  11. Brandt, C.; Nolte, H.; Henschke, S.; Engstrom Ruud, L.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H. G.; Hess, M. E.; Gunther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Kruger, M.; Bruning, J. C.: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation. Cell 175 (5), S. 1321 - 1335 e20 (2018)
  12. Catterson, J. H.; Khericha, M.; Dyson, M. C.; Vincent, A. J.; Callard, R.; Haveron, S. M.; Rajasingam, A.; Ahmad, M.; Partridge, L.: Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension. Curr Biol 28 (11), S. 1714 - 1724 e4 (2018)
  13. Collmann, F. M.; Pijnenburg, R.; Schneider, G.; Schafer, C.; Folz-Donahue, K.; Kukat, C.; Hoehn, M.: Imaging Reporter Strategy to Monitor Gene Activation of Microglia Polarisation States under Stimulation. J Neuroimmune Pharmacol 13 (3), S. 371 - 382 (2018)
  14. Donertas, H. M.; Fuentealba Valenzuela, M.; Partridge, L.; Thornton, J. M.: Gene Expression-Based Drug Repurposing to Target Ageing. Aging Cell, S. e12819 (2018)
  15. Graef, M.: Membrane tethering by the autophagy ATG2A-WIPI4 complex. Proc Natl Acad Sci U S A 115 (42), S. 10540 - 10541 (2018)
  16. Graef, M.: Lipid droplet-mediated lipid and protein homeostasis in budding yeast. FEBS Lett (2018)
  17. Kauppila, J. H. K.; Bonekamp, N. A.; Mourier, A.; Isokallio, M. A.; Just, A.; Kauppila, T. E. S.; Stewart, J. B.; Larsson, N. G.: Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46 (13), S. 6642 - 6669 (2018)
  18. Matic, S.; Jiang, M.; Nicholls, T. J.; Uhler, J. P.; Dirksen-Schwanenland, C.; Polosa, P. L.; Simard, M. L.; Li, X.; Atanassov, I.; Rackham, O. et al.; Filipovska, A.; Stewart, J. B.; Falkenberg, M.; Larsson, N. G.; Milenkovic, D.: Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 9 (1), S. 1202 (2018)
  19. McCann, B. J.; Cox, A.; Gammage, P. A.; Stewart, J. B.; Zernicka-Goetz, M.; Minczuk, M.: Delivery of mtZFNs into Early Mouse Embryos. Methods Mol Biol 1867, S. 215 - 228 (2018)
  20. Medeiros, T. C.; Thomas, R. L.; Ghillebert, R.; Graef, M.: Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation. J Cell Biol (2018)
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