Publications 2019

Journal Article

  1. Reckzeh, E. S.; Karageorgis, G.; Schwalfenberg, M.; Ceballos, J.; Nowacki, J.; Stroet, M. C.M.; Binici, A.; Knauer, L.; Brand, S.; Choidas, A. et al.; Strohmann, C.; Ziegler, S.; Waldmann, H.: Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth. Cell Chemical Biology 26, pp. 1 - 41 (2019)
  2. Nass Kovacs, G.; Colletier, J.-P.; Grünbein, M. L.; Yang, Y.; Stensitzki, T.; Batyuk, A.; Carbajo, S.; Doak, R. B.; Ehrenberg, D.; Foucar, L. et al.; Gasper, R.; Gorel, A.; Hilpert, M.; Kloos, M.; Koglin, J. E.; Reinstein, J.; Roome, C. M.; Schlesinger, R.; Seaberg, M.; Shoeman, R. L.; Stricker, M.; Boutet, S.; Haacke, S.; Heberle, J.; Heyne, K.; Domratcheva, T.; Barends, T. R.M.; Schlichting, I.: Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nature Communications 10 (1), 3177, pp. 1 - 17 (2019)
  3. Raisch, T.; Chang, C.-T.; Levdansky, Y.; Muthukumar, S.; Raunser, S.; Valkov, E.: Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation. Nature Communications 10 (1), 3173, pp. 1 - 14 (2019)
  4. Alex, A.; Piano, V.; Polley, S.; Stuiver, M.; Voss, S.; Ciossani, G.; Overlack, K.; Voss, B.; Wohlgemuth, S.; Petrovic, A. et al.; Wu, Y.-W.; Selenko, P.; Musacchio, A.; Maffini, S.: Electroporated recombinant proteins as tools for in vivo functional complementation, imaging, and chemical biology. eLife 8, e48287, pp. 1 - 50 (2019)
  5. Laraia, L.; Friese, A.; Corkery, D. P.; Konstantinidis, G.; Erwin, N.; Hofer, W.; Karatas, H.; Klewer, L.; Brockmeyer, A.; Metz, M. et al.; Schölermann, B.; Dwivedi, M.; Li, L.; Rios-Munoz, P.; Köhn, M.; Winter, R.; Vetter, I. R.; Ziegler, S.; Janning, P.; Wu, Y.-W.; Waldmann, H.: The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nature Chemical Biology 15 (7), pp. 710 - 720 (2019)
  6. Škopić, M. K.; Götte, K.; Gramse, C.; Dieter, M.; Pospich, S.; Raunser, S.; Weberskirch, R.; Brunschweiger, A.: Micellar Brønsted Acid Mediated Synthesis of DNA-Tagged Heterocycles. Journal of the American Chemical Society 141 (26), pp. 10546 - 10555 (2019)
  7. Garivet, G.; Hofer, W.; Konitsiotis, A.; Klein, C.; Kaiser, N.; Mejuch, T.; Fansa, E. K.; Alsaabi, R.; Wittinghofer, A.; Bastiaens, P. I. H. et al.; Waldmann, H.: Small-Molecule Inhibition of the UNC-Src Interaction Impairs Dynamic Src Localization in Cells. Cell Chemical Biology 26 (6), pp. 842 - 851 (2019)
  8. Friese, A.; Ursu, A.; Hochheimer, A.; Schöler, H. R.; Waldmann, H.; Bruder, J. M.: The Convergence of Stem Cell Technologies and Phenotypic Drug Discovery. Cell Chemical Biology, pp. 1 - 17 (2019)
  9. Kaiser, N.; Corkery, D.; Wu, Y.; Laraia, L.; Waldmann, H.: Modulation of autophagy by the novel mitochondrial complex I inhibitor Authipyrin. Bioorganic & Medicinal Chemistry 27 (12 (SI)), pp. 2444 - 2448 (2019)
  10. Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie, pp. 1 - 14 (2019)
  11. Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie International Edition, pp. 1 - 14 (2019)
  12. Corno, A.; Chiroli, E.; Gross, F.; Vernieri, C.; Matafora, V.; Maffini, S.; Cosentino Lagomarsino, M.; Bachi, A.; Ciliberto, A.: Cellular response upon proliferation in the presence of an active mitotic checkpoint. Life Science Alliance 2 (3), e201900380, pp. 1 - 16 (2019)
  13. Förster, T.; Shang, E.; Shimizu, K.; Sanada, E.; Schölermann, B.; Hübecker, M.; Hahne, G.; Pascual Lopez-Alberca, M.; Janning, P.; Watanabe, N. et al.; Sievers, S.; Giordanetto, F.; Shimizu, T.; Ziegler, S.; Osada, H.; Waldmann, H.: 2-Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation. European Journal of Organic Chemistry, pp. 1 - 12 (2019)
  14. Wagner, T.; Merino, F.; Stabrin, M.; Moriya, T.; Antoni, C.; Apelbaum, A.; Hagel, P.; Sitsel, O.; Raisch, T.; Prumbaum, D. et al.; Quentin, D.; Roderer, D.; Tacke, S.; Siebolds, B.; Schubert, E.; Shaikh, T. R.; Lill, P.; Gatsogiannis, C.; Raunser, S.: SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM. Communications Biology 2, 218, pp. 1 - 13 (2019)
  15. Roderer, D.; Raunser, S.: Tc Toxin Complexes: Assembly, Membrane Permeation, and Protein Translocation. Annual Review of Microbiology 73, pp. 11.1 - 11.19 (2019)
  16. Gersch, M.; Wagstaff, J. L.; Toms, A. V.; Graves, B.; Freund, S. M. V.; Komander, D.: Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity. Molecular Cell 74 (3), pp. 436 - 451 (2019)
  17. Tanaka, Y.; Kato, S.; Stabrin, M.; Raunser, S.; Matsui, T.; Gatsogiannis, C.: Cryo-EM reveals the asymmetric assembly of squid hemocyanin. IUCrJ 6 (3), pp. 426 - 437 (2019)
  18. Schneidewind, T.; Kapoor, S.; Garivet, G.; Karageorgis, G.; Narayan, R.; Vendrell Navarro, G.; Antonchick, A. P.; Ziegler, S.; Waldmann, H.: The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented Chemotype. Cell Chemical Biology 26 (4), pp. 512 - 523 (2019)
  19. Marabelli, C.; Marrocco, B.; Pilotto, S.; Chittori, S.; Picaud, S.; Marchese, S.; Ciossani, G.; Forneris, F.; Filippakopoulos, P.; Schoehn, G. et al.; Rhodes, D.; Subramaniam, S.; Mattevi, A.: A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Reports 27 (2), pp. 387 - 399 (2019)
  20. Xu, C.; Loh, C. C. J.: A Multistage Halogen Bond Catalyzed Strain-Release Glycosylation Unravels New Hedgehog Signaling Inhibitors. Journal of the American Chemical Society 141 (13), pp. 5381 - 5391 (2019)
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