Publications 2012

Aghdam, S. Y.; Eming, S. A.; Willenborg, S.; Neuhaus, B.; Niessen, C. M.; Partridge, L.; Krieg, T.; Brüning, J. C.;
Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochem Biophys Res Commun 421, 197-202 (2012)
Ahlqvist, K. J.; Hämäläinen, R. H.; Yatsuga, S.; Uutela, M.; Terzioglu, M.; Götz, A.; Forsström, S.; Salven, P.; Angers-Loustau, A.; Kopra, O. H.; Tyynismaa, H.; Larsson, N.-G.; Wartiovaara, K.; Prolla, T.; Trifunovic, A.; Suomalainen, A.;
Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in polg mutator mice. Cell Metab 15, 100-109 (2012)
Alic, N.; Hoddinott, M. P.; Foley, A.; Slack, C.; Piper, M. D.; Partridge, L.;
Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies. PLoS ONE 7, (2012)
Almajan, E. R.; Richter, R.; Paeger, L.; Martinelli, P.; Barth, E.; Decker, T.; Larsson, N.-G.; Kloppenburg, P.; Langer, T.; Rugarli, E. I.;
AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival. J. Clin. Invest. 122, 4048-4058 (2012)
Antebi, A.;
Regulation of longevity by the reproductive system. Experimental Gerontology, (2012)
Barzilai, N.; Guarente, L.; Kirkwood, T. B. L.; Partridge, L.; Rando, T. A.; Slagboom, P. E.;
The place of genetics in ageing research. Nature Reviews Genetics 13, 589-594 (2012)
Cocheme, H. M.; Logan, A.; Prime, T. A.; Abakumova, I.; Quin, C.; McQuaker, S. J.; Patel, J. V.; Fearnley, I. M.; James, A. M.; Porteous, C. M.; et al., ;
Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nature Protocols 7, 946-958 (2012)
Feldmeyer, N.; Wabnitz, G.; Leicht, S.; Luckner-Minden, C.; Schiller, M.; Franz, T.; Conradi, R.; Kropf, P.; Müller, I.; Ho, A. D.; Samstag, Y.; Munder, M.;
Arginine deficiency leads to impaired cofilin dephosphorylation in activated human T lymphocytes. Int. Immunol. 24, 303-313 (2012)
Franz, T.; Li, X.;
The OASIS® HLB µElution Plate as a one-step platform for manual high-throughput in-gel digestion of proteins and peptide desalting. Proteomics 12, 2487-2492 (2012)
Freyer, C.; Cree, L. M.; Mourier, A.; Stewart, J. B.; Koolmeister, C.; Milenkovic, D.; Wai, T.; Floros, V. I.; Hagström, E.; Chatzidaki, E. E.; Wiesner, R. J.; Samuels, D. C.; Larsson, N.-G.; Chinnery, P. F.;
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nature Genetics 44, 1282-1285 (2012)
Gioti, A.; Wigby, S.; Wertheim, B.; Schuster, E.; Martinez, P.; Pennington, C. J.; Partridge, L.; Chapman, T.;
Sex peptide of Drosophila melanogaster males is a global regulator of reproductive processes in females. Proceedings Biological Sciences / the Royal Society 279, 4423-4432 (2012)
Lee, S.; Sterky, F. H.; Mourier, A.; Terzioglu, M.; Cullheim, S.; Olson, L.; Larsson, N.-G.;
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum Mol Genet 21, 4827-4835 (2012)
Naess, K.; Barbaro, M.; Bruhn, H.; Wibom, R.; Nennesmo, I.; Döbeln, von, U.; Larsson, N.-G.; Nemeth, A.; Lesko, N.;
Complete Deletion of a POLG1 Allele in a Patient with Alpers Syndrome. Jimd Reports 4, 67-73 (2012)
Neuhaus, B.; Niessen, C. M.; Mesaros, A.; Withers, D. J.; Krieg, T.; Partridge, L.;
Experimental analysis of risk factors for ulcerative dermatitis in mice. Experimental Dermatology 21, 712-713 (2012)
Niccoli, T.; Partridge, L.;
Ageing as a risk factor for disease. Current Biology CB 22, R741-R752 (2012)
Papatheodorou, I.; Ziehm, M.; Wieser, D.; Alic, N.; Partridge, L.; Thornton, J. M.;
Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. PLoS ONE 7, (2012)
Partridge, L.;
Diet and healthy aging. The New England Journal of Medicine 367, 2550-2551 (2012)
Rogers, I.; Kerr, F.; Martinez, P.; Hardy, J.; Lovestone, S.; Partridge, L.;
Ageing Increases Vulnerability to Aβ42 Toxicity in Drosophila. PLoS ONE 7, (2012)
Schaedel, O.N.; Gerisch, B.; Antebi, A.; Sternberg, P.W.;
Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood. PLoS Biology 10, (2012)
Selman, C.; Partridge, L.;
A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice. Cell Cycle 11, 17-18 (2012)
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