Yearbook 2013

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
During development cardiac morphogenesis relies on the concerted activity of several growth factor receptors including the proto oncogene ERBB2. In adults, its cardiotoxicity causes severe side effects in anti-ERBB2 cancer therapies. Therefore we developed a transgenic zebrafish line to elucidate the role of ErbB2 signaling in cardiomyocytes. Using this novel tool combined with state-of-the-art microscopy, we were able to identify ErbB2 as a mediator of remodeling of the contractile machinery, an unexpected mechanism with potentially important implications to human health. more
Yellow strips on sketches, models and artefacts bespeak of the Qing empire’s interest in material production. Around 1700, court officials systematically employed these predecessors of modern post-its notes to communicate the design of artefacts of all kinds. The technical and aesthetic documents became the empirical basis upon which Chinese scholar-officials, sophisticating managerial methods, debated the validity of standards and procedures. Alongside ideals and realization, the materiality of planning unfolds how knowledge and action were negotiated to make things work. more
The ability to read is a fundamental prerequisite for participation in modern, information-based societies. Learning to read is a long and complex process, however, and one that not all students master with ease – as studies such as PISA have shown. Individuals with functional illiteracy can find themselves excluded from many areas of life and work. The Max Planck Research Group REaD investigates the underlying structure of students’ reading skills as well as the development of these skills during childhood and adolescence. It aims to find out how reading deficits can be addressed effectively. more
Our social environments and the problems they entail can be utterly complex. But what does this mean for our decision behavior? Do complex problems necessarily require complex cognitive machinery? Researchers of the Center for Adaptive Rationality at the Max Planck Institute for Human Development show that also in social environments decision-making can benefit from simple rules of thumb, or heuristics, as well as from relying on just a few good pieces of information. more
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