Research report 2012 - Max Planck Institute for Plant Breeding Research

Regulatory roles of plant TFIIH protein kinases

Authors
Koncz, Csaba
Departments
Abteilung Entwicklungsbiologie der Pflanzen
Summary
RNA polymerase II transcribes protein coding and several classes of regulatory RNAs in multicellular organisms. The C-terminal domain of the RNAPII largest subunit, RNAPII-CTD, carries conserved heptapeptide repeats that are phosphorylated at different residues by a protein kinase cascade in Arabidopsis. Recent studies start to reveal how phosphorylation of the RNAPII-CTD by TFIIH-associated protein kinases regulates growth and development via coordinated control of transcription, cell cycle and biogenesis of microRNAs and small silencing siRNAs.

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