2013, Max Planck Institute for Informatics
Kalinina, Olga; Pfeifer, Nico
After more than 25 years of research on HIV and AIDS, there is still no approved therapy that would eradicate the virus from an infected patient. At the Max Planck Institute for Informatics, new bioinformatics methods have been developed that, in a patient-specific manner, predict the applicability of a new class of drugs, which block the entry of the virus into human cells. They have investigated the properties of viral and human proteins participating in viral cell entry, and showed how to improve antibody test panels for HIV vaccine development.