Research report 2011 - Max Planck Institute for Molecular Biomedicine
How leukocytes overcome the blood vessel wall
Schulte, Dörte; Broermann, Andre; Nottebaum, Astrid; Kiefer, Friedemann, Butz, Stefan; Vestweber, Dietmar
Vaskuläre Zellbiologie (Prof. Dr. Dietmar Vestweber)
SummaryResearchers at the MPI for Molecular Biomedicine could define one of two possible routes as the major pathway for leukocytes that leave the blood system and enter into inflamed tissue. In addition, they could identify a switch that allows to open the passage through the blood vessel wall. These results could lead to the development of novel therapeutics to treat inflammation.