Research report 2011 - Max Planck Institute of Neurobiology
Guidance cues for growing nerves
Dudanova, Irina; Klein, Rüdiger
Molekulare Neurobiologie (Prof. Dr. Rüdiger Klein)
SummaryOur movements are controlled by nerve cells located in the spinal cord. Before birth, these cells have to be connected with the correct muscles, some of which are situated far away from the spinal cord, like the muscles of the lower leg. To reach their destination, the processes of nerve cells have to cover large distances, growing through different tissues. How do they find their way in this complex environment? Scientists from the Max Planck Institute of Neurobiology use genetic and cell biological methods to study the molecular signals that help the growing nerves navigate through the body.