Research report 2011 - Max Planck Institute of Molecular Cell Biology and Genetics

Cutting-edge microscopy cutting with light - SPIM

Authors
Huisken, Jan
Departments
Quantitative microscopy of zebrafish organogenesis (Huisken Lab)
Summary
Light sheet microscopy has contributed substantially to the emerging field of real-time developmental biology. Advantages of new systems are low photo-toxicity and high-speed multiview acquisition, which make them a popular choice for studies of organ morphogenesis in model organisms. A variety of light sheet microscopes have emerged for the noninvasive imaging of specimens ranging from single molecules to cells, tissues, and entire embryos. This enables researchers to watch developmental events occur in real time in an entire embryo, and to understand how cells form tissues and organs.

For the full text, see the German version.

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