Research report 2011 - Max Planck Institute of Biochemistry

Immune system protection can cost your health

Schmidt-Supprian, Marc
Molekulare Immunologie und Signaltransduktion
Our bodies are constantly under attack by hostile microorganisms, such as bacteria and viruses. Immune cells can identify foreign microbial components through a host of cell surface receptors. These receptors relay signals to the nucleus, where transcription factors activate the expression of genes whose protein products help fight the invaders. Misguidance of immune mechanisms can result in autoimmunity and leukemias or lymphomas. Researchers employ genetic mouse models to understand how signal transduction orchestrates immune responses and how its deregulation causes disease.

For the full text, see the German version.

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