Research report 2009 - Max Planck Institute of Molecular Plant Physiology
Lipid-Rafts – Specialized Areas of the Plasma Membrane
Schulze, Waltraud; Kierszniowska, Sylwia
Signaltransduktion und Proteomik (Emmy-Nöther-Gruppe) (Dr. Waltraud Schulze)
MPI für molekulare Pflanzenphysiologie, Potsdam
SummaryPlasma membranes are dynamic compartments with key functions in solute transport, cell shape and in communication between cells and the environment. In all organisms plasma membranes are compartmented into sterol-rich microdomains, which are defined by their resistance to treatment with non-ionic detergents and have specific roles in signal transduction and regulatory processes. This microdomains are called "lipid rafts”. Now the composition of true sterol-dependent 'raft proteins' and sterol-independent 'non-raft' proteins was for the first time experimentally clearly defined.