Medical Bioinformatics: Molecular Modeling of Diseases and Analysis of Relevant Protein Interactions

Proteins are involved with many life processes in cells. The knowledge about their complex interplay on the molecular level provides important insights into diseases and cellular mechanisms. Currently, experimentally determined protein interactions are collected worldwide in databases. Therefore, bioinformaticians at the Max Planck Institute for Informatics developed an easy-to-use Internet-based system, which facilitates the global access to the data. Bioinformatics methods are also applied in detailed studies of protein interactions and their 3D structure and disease-relevant function.