Research report 2010 - Max Planck Institute for Biophysical Chemistry
Electron spins as probes for biomolecules
Tkach, Igor und Bennati, Marina
Elektronenspinresonanz-Spektroskopie (PD Dr. Marina Bennati)
MPI für biophysikalische Chemie, Göttingen
SummaryUnpaired electrons possess a magnetic moment, which is about three orders of magnitude larger than the one of a proton. This moment can be employed as a highly sensitive probe in EPR spectroscopic investigations to gain structural information at the atomic up to the nanometer scale. The experiments provide insights into structural changes of biomolecules during their functional states. We have developed and implemented multi-frequency EPR methodologies to investigate enzymatic reactions in proteins and oligonucleotides.